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>Journals >Revista Médica MD >Year 2018, Issue 2


Velarde-Ruiz VJA, Morales-Arambúla M, Coss-Adame E, Gómez-Escudero O, Flores-Rendón R, Vázquez-Elizondo G, Carmona-Sánchez RI, Icaza-Chavéz ME, Tamayo-de la Cuesta JL, Huerta-Iga F, Tapia-Calderón DK, García-Jiménez ES, Morel-Cerda EC, García-Zermeño KR, Remes-Troche JM
Prevalence of overlapping functional gastrointestinal disorders: results from a national study (SIGAME 2)
Rev Med MD 2018; 9.10 (2)

Language: Español
References: 20
Page: 106-112
PDF: 609.86 Kb.


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ABSTRACT

Introduction. Functional gastrointestinal disorders (FGIDs) are recognized as a group of diseases with altered gut-brain interaction but without organic abnormality. FGIDs are the most common diagnoses in gastroenterology consults. It is frequent to find patients that cannot be englobed in one FGID, namely overlap of these disorders. Research studies of the epidemiological behavior of these overlaps are very important to develop therapeutic targets that improve morbidity of these disorders. The aim of this study was to know the prevalence of overlap FGIDs in patients that attended a specialty consultation in different states of the country.
Material and Methods. A descriptive, transversal study based on a survey about gastrointestinal symptoms in Mexico (SIGAME second version) was conducted. It consisted of an online questionnaire that included 184 items inquiring on clinical characteristics, resource utilization and prescription of patients attending consultation with 11 different Mexican gastroenterologists among 8 different states in Mexico. The objective was to recollect at least 1000 cases between January to May 2017.
Results. We included 925 patients, among who 71% were women. The final study population was 836. We found positive answers for gastroesophageal reflux disease (GERD) in 372 (44.4%) subjects; 247 individuals (29.5%) satisfied irritable bowel syndrome (IBS) criteria,finally, 87 patients (10.4%) fulfilled dyspepsia criteria. GERD-IBS complex was present in 106 patients; GERD-Dyspepsia was found in 68 subjects; and IBS-Dyspepsia was identified in 55 people. Finally, triple overlap (GERD-Dyspepsia-IBS) was found in 26 patients.
Discussion. In Mexico, it is frequent to find gastrointestinal symptoms overlap from different FGIDs. In this survey, the main FGID was GERD, which coexisted with another disease in nearly half of patients. A correct approach to individual gastrointestinal symptoms is important in order to define the best treatment strategy to lower the morbidity of FGIDs


Key words: dyspepsia, functional gastrointestinal disorders, irritable bowel syndrome, overlap, reflux.


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