2018, Number 61
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ABSTRACTChronic kidney disease is the progressive and irreversible decrease of the glomerular filtration. Because of this, the onset of hormonal and metabolic changes is determined. Among the changes, there are vitamin D, calcium, phosphorus, parathyroid hormone and the acid-base balance. This generates multiple stimuli in the parathyroid gland and develops secondary hyperparathyroidism. Brown tumor represents one of the most common complications of this issue. Hereby, a bibliographic review is made, which encompasses the connections between chronic kidney disease and hyperparathyroidism, since the clinical case of a female patient, with 35 years old, came up. The female presents a record of CKD and a rise in the bilateral intraoral volume in the anterior lower-left area and upper right premolars, without any symptoms, in a slightly violaceous color with telangiectasias on the surface, soft at palpation, with a sessile base, 3 months of evolution and a slow growth. When the patient was directly interviewed, she reported weight loss, general malaise, fatigue, a change in skin color and excessive transpiration. A differential diagnosis is made and it establishes a definite histological diagnosis for the brown tumor of the secondary hyperparothyroidism.
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