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Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México

2019, Number 2

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Rev Mex Oftalmol 2019; 93 (2)

Corneal morphological patterns detected by spectral domain optical coherence tomography in patients with infectious keratitis

Aguilar-Pérez MA, Fernández-Vizcaya O, Alegría-Gómez ED, Velasco-Ramos R, Baca-Lozada O, Pérez-Cano HJ, Saldaña-Rivera E, Pacheco-del Valle C

Language: Spanish
References: 18
Page: 63-68
PDF size: 266.45 Kb.


ABSTRACT

Objective: To distinguish the existence of characteristic corneal morphological patterns, detected by spectral domain optical coherence tomography (OCT) in patients with infectious keratitis. Methods: Descriptive, cross-sectional, prospective and observational study in patients with infectious keratitis. OCT, clinical photographs and sample for confirmation of the causative agent by PCR were taken. The images were analyzed for characteristic patterns for each type of causative agent. Results: We included 19 patients with infectious keratitis with available OCT images for observation, analysis and classification. We found patterns that helped us differentiate bacterial versus fungal etiologies based on the hyperreflectivity patterns observed. Conclusions: OCT is a useful test as an aid to differentiate the causative agent of infectious keratitis and to evaluate the involvement of corneal tissue.


REFERENCES

  1. Whitcher JP, Srinivasan M, Upadhyay MP. Corneal Blidness: a global perspective. Bull World Health Organ. 2001;79:214-21.

  2. Arrúa M, Laspina F, Samudio M. Queratitis infecciosas. Características clínicas y microbiológicas. Período 2003-2006, Mem Inst Investig Cienc Salud. 2008;6(1):5-14.

  3. American Academy of Ophthalmology Cornea/External Disease Panel. Preferred Practice Pattern Guidelines. Bacterial Keratitis. San Francisco, CA: American Academy of Ophthalmology; 2013.

  4. Keay L, Edwards K, Naduvilath T, Taylor HR, Snibson GR, Forde K, et al. Microbial keratitis predisposing factors and morbidity. Ophtalmology. 2006;113(1):109-16.

  5. Mantapoulos D, Cruzat A, Hamrah P. In vivo Imaging of Corneal Inflammation: New Tools for Clinical Practice and Research. Semin Ophthalmol. 2010;25(5-6):178-85.

  6. Julio C. Hernández-Camarena, Enrique O. Graue-Hernández, Patricia Chirinos-Saldaña Queratitis infecciosas: tendencias microbiológicas y sensibilidad a antibióticos. Rev Mex Oftalmol. 2012;86(4):213-22.

  7. Ramos JL, Li Y, Huang D. Clinical and research applications of anterior segment optical coherence tomography-a review. Experiment Ophthalmol. 2009;37(1):81-9.

  8. Belin M, Khachikian S, McGhee C. New Technology in corneal imaging. International Ophtalmology Clinics. 2010;50(3):177-89.

  9. Tahiri Joutei Hassani R, Liang H, El Sanharawi M, Brasnu E, Kallel S, Labbé A, Baudouin C. En-face optical coherence tomography as a novel tool for exploring the ocular surface: a pilot comparative study to conventional b-scans and in vivo confocal microscopy. The Ocular Surface. 2014;12(4):286-306.

  10. Konstantopoulos A, Kuo J, Anderson D, Hossain P. Assessment of the use of anterior segment optical coherence tomography in microbial keratitis. Am J Ophthalmol. 2008;146(4):534-42.

  11. Fernández-Viazcaya O, Velasco-Ramos R, Baca-Lozada O, Babayan-Sosa A. Análisis descriptivo y seguimiento de colgajos conjuntivales mediante Tomografía de Coherencia óptica coherente de segmento anterior. Boletín Oftalmológico de Nuestra Señora de la Luz. Año LXXXIII, Tomo LXII. 2009;223:23-30.

  12. Han SB, Liu YC, Noriega KM, Mehta JS. Applications of Anterior Segment Optical Coherence Tomography in Cornea and Ocular Surface Diseases. J Ophtalmol. 2016;2016:4971572.

  13. Konstantopoulos A, Yadegarfar G, Fievez M, Anderson DF, Hossain P. In vivo quantification of bacterial keratitis with optical coherence tomography. Invest Ophthalmol Vis Sci. 2011;52(2):1093-7.

  14. Jancevski M, Foster CS. Anterior Segment Optical Coherence Tomography. Semin Ophtalmol. 2010;25(5-6):317-23.

  15. Yokogawa H, Kobayashi A, Yamazaki N, Sugiyama K. In Vivo Imaging of Coin_Shaped Lesions in Cytomegalovirus Corneal Endothelitis by Anterior Segment Optical Coherence Tomography. Cornea, 2014;33(12):1332-5.

  16. W. Soliman, Fathalla A, El-Sebaity M. Graefes. Spectral domain anterior segment optical coherence tomography in microbial keratitis. Arch Clin Exp Ophthalmol. 2013;251:549-53.

  17. Abbouda A, Estrada AV, Rodríguez AE, Alió JL. Anterior segment optical coherence tomography in evaluation of severe fungal keratitis infectios treated by corneal crosslinking. Eur J Ophthalmol. 2014;24(3):320-4.

  18. Takezawa Y, Suzuki T, Shiraishi A. Obeervation of Retrocorneal Plaques in Patients With Infectious Keratitis Using Anterior Segment Optical Coherence Tomography. Cornea. 2017;36(10):1-6.




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