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Revista Mexicana de Oftalmología

Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México
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2018, Number 6

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Rev Mex Oftalmol 2018; 92 (6)

Comparison of a thermoelectric heat device, tea tree oil shampoo eyelid scrubs and conventional treatment in elderly patients with meibomian gland dysfunction

Hernández-Martínez N, Fernández-Vizcaya O, Pacheco-Del Valle C, Velasco-Ramos R, Babayán-Sosa A, Alegría-Gómez E, Raya-Hernández D, Baca-Lozada O
Full text How to cite this article

Language: Spanish
References: 18
Page: 278-285
PDF size: 209.85 Kb.


Key words:

Meibomian glands, Eyelid diseases, Dry eye syndromes, Dysfunction, Comparative study.

ABSTRACT

Purpose: to compare the efficacy between a thermoelectric heat device (MiBoFlo Thermoflo ®), tea tree shampoo eyelid scrubs and baby shampoo eyelid scrubs in elderly patients with meibomian gland dysfunction (MGD). Materials and methods: prospective, interventional, longitudinal and comparative study. Forty-one elderly patients (82 eyes) were included. Patients were divided in three groups. Group I (n=30): patients received 3 sessions with Thermoflo. Group II (n=26): tea tree shampoo eyelid scrubs. Group III (n=26): control, with baby shampoo. Ophthalmologic examination included basal secretion test with topical anesthesia, tear break-up time (TBUT), ocular surface fluorescein staining with the Oxford scheme, meibomian gland (MG) assessment (meibum quality and expressibility) and Ocular Surface Disease Index (OSDI) questionnaire. Evaluations were made at baseline, 4 and 8 weeks post-treatment. Repeated measures ANOVA with Greenhouse-Geisser correction was used to determine significant changes between groups. Results: There were statistically significant changes in Oxford, meibum quality and gland expressibility between the groups. OSDI score and TBUT showed improvement, but were not statistically significant. Conclusion: Apparently Thermoflo and tea tree shampoo treatments were superior for the improvement of signs and symptoms associated with MGD. Thermoflo seems superior in improving obstructive MGD due to greater gland expressibility.


REFERENCES

  1. Friedland BR, Fleming CP, Blackie CA, Korb DR. A novel thermodynamic treatment for meibomian gland dysfunction. Current eye research. 2011;36(2):79-87.

  2. Nakayama N, Kawashima M, Kaido M, Arita R, Tsubota K. Analysis of Meibum Before and After Intraductal Meibomian Gland Probing in Eyes With Obstructive Meibomian Gland Dysfunction. Cornea. 2015;34(10):1206-8.

  3. Jester JV, Parfitt GJ, Brown DJ. Meibomian gland dysfunction: hyperkeratinization or atrophy? BMC ophthalmology. 2015;15 Suppl 1:156.

  4. Baudouin C, Messmer EM, Aragona P, Geerling G, Akova YA, Benitez-Del-Castillo J, et al. Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction. Br J Ophthalmology. 2016;100(3):300-6. PubMed PMID: 26781133. Pubmed Central PMCID: 4789719.

  5. Nichols KK, Foulks GN, Bron AJ, Glasgow BJ, Dogru M, Tsubota K, et al. The international workshop on meibomian gland dysfunction: executive summary. Investigative ophthalmology & visual science. 2011;52(4):1922-9.

  6. Cárdenas Díaz T, Hernández López I, Guerra Almaguer M, Cruz Izquierdo D, Miranda Hernández I, Montero Díaz E. Conceptos actuales en la disfunción de las glándulas de Meibomio. Revista Cubana de Oftalmología. 2014;27(2):264-71.

  7. Alghamdi YA, Mercado C, McClellan AL, Batawi H, Karp CL, Galor A. Epidemiology of Meibomian Gland Dysfunction in an Elderly Population. Cornea. 2016;35(6):731-5.

  8. Thode AR, Latkany RA. Current and Emerging Therapeutic Strategies for the Treatment of Meibomian Gland Dysfunction (MGD). Drugs. 2015;75(11):1177-85.

  9. Chhadva P, Goldhardt R, Galor A. Meibomian Gland Disease: The Role of Gland Dysfunction in Dry Eye Disease. Ophthalmology. 2017;124(11S):S20-S6.

  10. Qiao J, Yan X. Emerging treatment options for meibomian gland dysfunction. Clin Ophthal. 2013;7:1797-803.

  11. Lane SS, DuBiner HB, Epstein RJ, Ernest PH, Greiner JV, Hardten DR, et al. A new system, the LipiFlow, for the treatment of meibomian gland dysfunction. Cornea. 2012;31(4):396-404.

  12. Koo H, Kim TH, Kim KW, Wee SW, Chun YS, Kim JC. Ocular surface discomfort and Demodex: effect of tea tree oil eyelid scrub in Demodex blepharitis. Journal of Korean medical science. 2012;27(12):1574-9.

  13. Geerling G, Tauber J, Baudouin C, Goto E, Matsumoto Y, O’Brien T, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction. Investigative ophthalmology & visual science. 2011;52(4):2050-64.

  14. Carson CF, Hammer KA, Riley TV. Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clin Microbiol Rev. 2006;19(1):50-62.

  15. website TMcr. TearScience. MiBo clinical research website http://mibomedicalgroup. com/clinical-research/2016 [cited 2016 April 2.

  16. Blackie CA, Carlson AN, Korb DR. Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review. Curr Op Ophthalmol. 2015;26(4):306-13.

  17. Zhao Y, Veerappan A, Yeo S, Rooney DM, Acharya RU, Tan JH, et al. Clinical Trial of Thermal Pulsation (LipiFlow) in Meibomian Gland Dysfunction With Preteatment Meibography. Eye Contact Lens. 2016;42(6):339-46.

  18. Alegría-Gómez ED ., Baca-Lozada O.. Evaluación de la película lagrimal. En: Córnea Médica. 1.a ed. México: Elsevier; 2015. p. 43-51.




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Rev Mex Oftalmol. 2018;92