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Órgano Oficial del Hospital Angeles Health System

2004, Number 3

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Acta Med 2004; 2 (3)

Effect of the transdermic hormonal replacement in postmenopause on the body mass index and the leptin level

Galván RE, Saucedo R, Hernández M, Mora C, Basurto L, Zárate A

Language: Spanish
References: 22
Page: 147-149
PDF size: 50.60 Kb.


ABSTRACT

Objective: To evaluate the effect of transdermal estradiol replacement (RHT) on leptin levels and body mass index (BMI) in postmenopausal women. Methods: Prospective study in 27 healthy hysterectomized postmenopausal women who received RHT twice at week (50 µg per day) during 3 months to evaluate any changes in leptin concentrations and BMI. Results: RHT had no effect on leptin levels and BMI. Serum leptin levels showed a positive correlation with BMI in all the subjects studied (rs =0.605, p ‹ 0.001). Conclusion: RHT did not modify leptin levels and BMI which in turn seemed to show a favorable effect of RHT in postmenopausal women.


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