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2017, Number 1

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Enf Infec Microbiol 2017; 37 (1)

Escherichia coli its resistance pattern in urine cultures of pediatric patients with urinary tract infection, in a tertiary level hospital

Guerrero BM, Mercado UMC, Luévanos VA, Martínez AP, Plascencia HA, Ulin OF
Full text How to cite this article

Language: Spanish
References: 11
Page: 14-17
PDF size: 197.61 Kb.


Key words:

urinary infection, Escherichia coli, resistance, antibiotics.

ABSTRACT

Introduction. Urinary tract infection (uti) in pediatric population ranks the third national place as a medical consult motive. Escherichia coli is the prevalent agent in 80% of cases.
Objective. To report the resistance antibiotic pattern of E. coli in isolates from children with community-acquired urinary tract infection.
Material and Methods. Descriptive, comparative study from January 1 to December 31 period in 2007 and 2015. Isolates of positive urine cultures to E. coli of patients with a diagnosis of urinary infection were included. Sensitivity and antibiotic resistance analyzes were performed.
Results. There were included 158 E. coli isolates of corresponding to 2007 and 82 to 2015. Resistance was significantly increased to cefepime, ceftriaxone and levofloxacin in 2015, but not for another antibiotics. The general percentage of resistance was about 10 to 50%. Phenotypically, 31.7% of the strains were esbl producers.
Conclusions. The prevalence of community-acquired pediatric UTI by E. coli in our hospital was 66 cases per 100 episodes. Antibiotics used empirically for this condition had an antibiotic resistance level greater than 30 percent.


REFERENCES

  1. American Academy of Pediatrics, Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, “Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial uti in febrile infants and children 2 to 24 months”, Pediatrics, 2011, 128 (3): 595-610.

  2. Montini, G., Tullus, K. y Hewitt, I., “Febrile urinary tract infections in children”, nejm, 2011, 365: 239-250.

  3. sinave-dge-Secretaría de Salud, México, Información epidemiológica de morbilidad, Anuario 2015, disponible en http://www.epidemiologia.salud.gob.mx/anuario/html/ morbilidad_nacional.htm/2015.

  4. Ismaili, K. y Wissing, K.M., “Characteristics of first urinary tract infection with fever in children a prospective clinical and imaging study”, Ped Infect Dis J, 2011, 30: 371-374.

  5. Crain, J.C., Simpson, J.M. et al., “Antibiotic prophylaxis and recurrent urinary tract infection in children”, nejm, 2009, 361: 1748-1759.

  6. Chávez, V.V., Gallegos, N.S. y Arce, S.A., “Patrones de resistencia antimicrobiana y etiología en infecciones urinarias no complicadas”, Gac Méd Mex, 2010, 146: 269-273.

  7. Aguirre, A.H., Plascencia, H.A., Rivera, M.C., Guerrero, B.M. y Murillo, N.V., “Resistencia de Escherichia coli en infecciones de vías urinarias en pacientes pediátricos del Hospital Civil de Guadalajara Fray Antonio Alcalde”, Enf Infec Microbiol, 2007, 27: 83-87.

  8. Calderón, J., Casanova, G., Galindo, A. et al., “Diagnóstico y tratamiento de las infecciones en vías urinarias: un enfoque multidisciplinario para casos no complicados”, Bol Med Hosp Infant Mex, 2013, 70: 3-10.

  9. Arredondo, J.L., Soriano, D., Solórzano, F. et al., “Etiología y tratamiento de infecciones de vías urinarias (utis) en niños”, Rev Enf Inf Ped, 2006, 19: 100-106.

  10. Arredondo, J.L. y Amábile, C.F., “High resistance prevalence towards ampicillin, co-trimoxazole and ciprofloxacin, among uropathogenic Escherichia coli isolates in Mexico City”, J Infect Developing Countries, 2008, 2: 350-353.

  11. Guajardo, C.E., González, P.M. y Ayala, G.J., “Resistencia antimicrobiana en la infección urinaria por Escherichia coli adquirida en la comunidad. ¿Cuál antibiótico voy a usar?”, Salud Pública Mex, 2009, 51: 155-158.




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Enf Infec Microbiol. 2017;37