Díaz ML, Rodríguez JB, León RY

Language: Spanish
References: 8
Page: 51-55
PDF size: 198.15 Kb.

ABSTRACT

Castleman's disease is an uncommon condition with similar frequency in both sexes, which can appear at any age. It is characterized by the growth of benign tumors of the lymphatic tissue, located more frequently in the mediastinum, stomach and neck and are less frequent in the axilla, pelvis and pancreas. Histologically, three varieties are described: the hyaline-vascular, the plasma-cellular and the mixed. A case of a 13-year-old patient with a history of congenital micro-spherocytosis and cytomegalovirus infection is presented. He had frequent admissions due to prolonged febrile syndrome; the last one occurred at age 11, when an increase in the size of ganglion chains appeared, predominantly intra-abdominal ganglia. A histological study was performed that reported Castleman's disease with diffuse lymph node involvement, in addition to chronic reactive hepatitis. Currently the patient is maintained with outpatient follow-up with hematological control and abdominal ultrasound, as well as treatment with vitamin therapy. This report is presented due to the low prevalence of this type of tumor in University Pediatric Hospital Paquito González Cueto of Cienfuegos.

REFERENCES

1. López A, Gázquez I, Martín A, Rubio M. Enfermedad de Castleman localizada en región cervical. An Med Interna (Madrid) [revista en Internet]. 2003 [citado 18 Feb 2018];20(12):[aprox. 2p]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-71992003001200012&lng=es [Buscar en Google Scholar]

2. Coca I, Ortega MV, Fernández E, Gavilán JC, Bermúdez F. Enfermedad de Castleman localizada: descripción de un caso y revisión de la literatura. An Med Interna (Madrid) [revista en Internet]. 2003 [citado 18 Feb 2018];20(10):[aprox. 3p]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-71992003001000009&lng=es [Buscar en Google Scholar]

3. Rodríguez H, Buchaca E, Machado I, Pérez G, Pérez D. Enfermedad de Castleman: Presentación de cinco casos. An Med Interna (Madrid) [revista en Internet]. 2005 [citado 19 Feb 2018];22(1):[aprox. 4p]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-71992005000100006&lng=es [Buscar en Google Scholar]

4. Sánchez de Toledo S, Fábrega C, Marhueenda X, Lucaya N, Torán N, Gross C, et al. Enfermedad de Castleman. Anales de Pediatría [revista en Internet]. 2005 [citado 23 Ene 2017];63(1):[aprox. 4p]. Disponible en: https://www.sciencedirect.com/science/article/pii/S1695403305701429 [Buscar en Google Scholar]

5. De Marchi G, De Vita S, Fabris M, Scott CA, Ferracioli G. Systemic connective tissue disease complicated by castleman´s disease: report of a case and review of the literature. Haematologica. 2004;89(4):ECR03 [Buscar en Google Scholar]

6. Puerto IM, Martínez IB, Ochoa MC. Folicular dendritic cell sarcoma arising from nodal hyaline-vascular. Castleman´s disease: Case Report. HAEMA. 2003;6(1):81-4 [Buscar en Google Scholar]

7. Altiparmak MR, Pamuk ON, Pamuk GE, Dogusny G. Secondary amyloidosis in castleman´s disease: review of the literature and report of a case. Ann Hematol. 2002;81(6):336-9 [Buscar en Google Scholar]

8. Avellaneda A, Pérez A, Allez P, Gutiérrez E, Izquierdo M. Percepción de las enfermedades raras por el médico de atención primaria. SEMERGEN [revista en Internet]. 2012 [citado 23 Dic 2018];1(7):[aprox. 11p]. Disponible en: http://www.enfermedades-raras.org/es/default.htm [Buscar en Google Scholar]