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2018, Number 2

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Enf Infec Microbiol 2018; 38 (2)

Primary autoimmune thrombocytopenia after influenza vaccine

Zúñiga CIR, Caro LJ, Rivera RLA, Nicolás ORE, Romero RM, Rivera HÁ
Full text How to cite this article

Language: Spanish
References: 9
Page: 64-66
PDF size: 155.01 Kb.


Key words:

thrombocytopenia, autoimmune disease, influenza vaccine, adjuvant, event associated with vaccination.

ABSTRACT

Idiopathic thrombocytopenic purpura (ITP) of acute type may occur after vaccination. Cases of ITP associated with influenza vaccine are rare. We describe the case of a 42-year-old female patient who presents nasal, vaginal and mucous bleeding two days after she was vaccinated against influenza. Severe plaquetopenia was found by laboratory. She was hospitalized and treated with danazol, prednisone and intravenous human gammaglobulin. The patient recovered satisfactorily.


REFERENCES

  1. Tishler, M., Levy, O. y Amit, M., “Immune thrombocytopenic purpura following influenza vaccination”, imaj, 2006, 8: 322-323.

  2. Ikegame, K., Kaida, K., Fujioka, T., Kawakami, M., Hasei, H. et al., “Idiopathic thrombocytopenic purpura after influenza vaccination in a bone marrow transplantation recipient”, Bone Marrow Transplantation, 2006, 38: 323-324.

  3. Mantadakis, E., Farmaki, E., Thomaidis, S., Tsalkidis, A. y Chatzimichael, A.A., “Case of immune thrombocytopenic purpura after influenza vaccination consequence or coincidence?”, J Pediatr Hematol Oncol, 2010, 32: 227-229.

  4. Shizuma, T., “Autoimmune hemolytic anemia following influenza virus infection or administration of influenza vaccine”, J Blood Disorders Transf, 2014, 5: 3.

  5. Nagasaki, J., Manabe, M., Ido, K., Ichihara, H., Aoyama, Y., Ohta, T., Furukawa, Y. y Mugitani, A. “Postinfluenza vaccination idiopathic thrombocytopenic purpura in three elderly patients”, Case Rep Hematol, 2016, 2016: 7913092.

  6. Secretaría de Salud, Manual de vacunación, Centro Nacional para la Salud de la Infancia y la Adolescencia, México, 2017, pp. 174-180.

  7. World Healh Organization (who), “Information sheet observed rate of vaccine reactions influenza vaccine. Global vaccine safety, immunization, vaccines and biological”, julio de 2012.

  8. Secretaría de Salud, Manual de eventos supuestamente atribuibles a la vacunación e inmunización, Centro Nacional para la Salud de la Infancia y la Adolescencia, México, 2014, pp. 55-64.

  9. Hamiel, U., Kventsel, I. y Youngster, I., “Recurrent immune thrombocytopenia after influenza vaccination: a case report”, Pediatrics, 2016, 138 (6): e20160124.




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C?MO CITAR (Vancouver)

Enf Infec Microbiol. 2018;38