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2019, Number 2

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Arch Med Fam 2019; 21 (2)

Correlation between Intima-media Thickness with Pulse Wave Velocity, and Ankle-Brachial Index in Subjects with Metabolic Syndrome

Guerrero-García C, Rubio-Guerra AF, Arana-Pazos KC, Maceda-Serrano A, Narváez-Rivera JL, Meneses-Acero I, Vargas AG

Language: Spanish
References: 12
Page: 45-49
PDF size: 151.19 Kb.


ABSTRACT

Background: Arterial stiffness is an independent predictor of cardiovascular mortality, pulse wave velocity (PWV) is the standard for measuring arterial stiffness. Ankle-brachial index (ABI) ‹ 0.9 triples the risk of cardiovascular death. The measurement of the intima-media thickness (IMT) of the carotid arteries has a predictive value for the appearance of vascular disease. Objective: To establish if the IMT correlates with the PWV and the ABI in subjects with metabolic syndrome. Method: 35 subjects with metabolic syndrome were evaluated. In all of them, PWV was determined with a piece of Arteriograph equipment. The IMT was determined by B-mode ultrasonography of the carotid arteries, with high resolution equipment using a 7.5 MHz linear transducer. The ABI was quantified with a 5 MHz Doppler device, according to the usual technique. The statistical methods used were the Fisher Exact Test and the Pearson correlation coefficient. Results: A significant correlation between the IMT with the PWV (r = 0.57, r2 = 0.32, p = 0.0006) was found. We did not find a correlation between the ABI and the IMT (r = -0.31, p = 0.08). When evaluating the risk of presenting increased IMT in patients with increased PWV, we found statistical significance (p = 0.033). Only one patient with PWV› 9 m / S presented IMT ≤ 0.9 mm. Conclusion: We found that PWV was significantly correlated with IMT in subjects with metabolic syndrome. The measurement of pulse wave velocity is a tool that provides valuable information in the overall assessment of the cardiovascular risk of these patients.


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