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Revista Médica Sinergia

2019, Number 05

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Revista Médica Sinergia 2019; 4 (05)

Update in gestational trophoblastic pathology: hydatidiform mole and neoplasias

Espinoza AA, Fernández VR, Solar VT

Language: Spanish
References: 25
Page: 44-59
PDF size: 357.96 Kb.


ABSTRACT

Gestational trophoblastic disease is composed of a range of rare pathologies associated with pregnancy, ranging from benign to malignant. It is important to make an opportune diagnosis through the use of ultrasound; supported with laboratory and imaging studies, histological and molecular studies. In general terms, the treatment of pre-malignant molar disease will consist of uterine evacuation. The use of chemotherapeutic and surgical interventions, together with the use of radiotherapy, could have an important role in the treatment of this entities as well as for the neoplastic trophoblastic diseases. The hormone human chorionic gonadotropin is a crucial biomarker to measure the progression, response to treatment and follow-up of these diseases. Thanks to the implementation of improvements in diagnosis and treatment, the clinical presentation and morbidity of the diseases has changed as the years go by.


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