Muñoz HE, Jiménez MC, Brenes CJP, Webb WK

Language: Spanish
References: 10
Page: 119-123
PDF size: 422.13 Kb.

ABSTRACT

Non-Hodgkin lymphomas are originated from mature lymphocytes B, T and natural killers (NK). There is a rare, less frequent subtype that develops from NK cells and T cytotoxic cells denominated “Extranodal NK/T-cell lymphoma, nasal type”. This subtype usually affects men, in Latin America and Southeast of Asia. Mean age of presentation is 40-50 years. It is characterized by a rapid progression and destruction of midline structures. B symptoms are rare. Diagnosis is made based on the pathological anatomy and immunohistochemistry positive for NK/T cells markers and the presence of Epstein Barr virus. Treatment requires a multidisciplinary management between hematology and otorhinolaryngology. The prognosis depends on the tumor stage at the moment the diagnosis is make and the presence of risk factors.

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