2019, Number 5
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ABSTRACTSporotrichosis is a mycosis caused by fungal species that are part of the Sporothrix schenckii complex. Epidemiological and molecular studies have found only six species of the Sporothrix schenckii complex that cause infections in humans. Some species of this complex have a relevant zoonotic potential for transmission to humans, and some others only have phytopathogenic properties. It is considered the most frequent form of subcutaneous mycosis in Mexico. The main mechanism of infection a wound with loss of continuity of the skin followed by contamination with the fungus Sporothrix spp. The main clinical manifestations are lymphangitic sporotrichosis, fixed skin manifestation and disseminated manifestation. The most useful laboratory procedures to confirm the diagnosis are the cultivation of specimens such as exudate and tissue, as well as the histopathological study. The parasitic manifestation is represented by yeasts in the tissue or exudates. The most useful medications for its treatment are potassium iodide and itraconazole. Prevention is difficult; however, the use of protective equipment during work activities can help prevent this condition.
Alba-Fierro CA, Pérez-Torres A, Toriello C, Pulido-Camarillo E, López-Romero E, Romo-Lozano Y, Gutiérrez- Sánchez G, Ruiz-Baca E. Immune response induced by an immunodominant 60 kDa glycoprotein of the cell wall of Sporothrix schenckii in two mice strains with experimental sporotrichosis. J Immunol Res. 2016;6525831.