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2006, Number 2

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Med Cutan Iber Lat Am 2006; 34 (2)

Hypopigmented blue nevus: an uncommon variant of blue nevus

González VMC, Val-Bernal JF, González-López MA, Armesto S, Martino M, Fernández-Llaca JH
Full text How to cite this article

Language: Spanish
References: 9
Page: 63-66
PDF size: 334.98 Kb.


Key words:

blue nevus, amelanotic blue nevus, hypopigmentade blue nevus.

ABSTRACT

Blue nevi are typically heavily melanin-pigmented macules or papules. Amelanotic or hypopigmented blue nevus is a rare variant of blue nevus that has morphologic features similar to ordinary blue nevus but is either amelanotic or minimally pigmented. The lesions are located throughout the body with predilection for the face, the back and the dorso of the hands and feet. Both sexes are affected with a female to male rate of aproximately 2:1 and there is a predilection for young patients. Histologically is characterized by a dermal proliferation of spindle-shaped cells with little or no obvious melanin.
We here report two cases of amelanotic (hypomelanotic) blue nevus. Recognition of amelanotic blue nevus is important because of the lack of pigmentation may result in clinical and pathologic diagnostic difficulty. The histological differential diagnosis includes dermatofibroma, scar, intradermal nevus, neurofibroma and desmoplastic melanoma.


REFERENCES

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  2. Weedon D. Lentigines, naevi and melanomas. In: Skin Pathology, 2nd edition. London : Churchill Livingstone, 2002:803-58.

  3. Carr S, See J, Wilkinson B, Kossard S. Hypopigmented common blue nevus. J Cutan Pathol 1997;24:494-8.

  4. Bhawan J, Cao SL. Amelanotic blue nevus. A variant of blue nevus [abstract]. J Cutan Pathol 1997;24:87

  5. Bhawan J, Cao SL. Amelanotic blue nevus: a variant of blue nevus. Am J Dermatopathol 1999;21:225-8.

  6. Zembowicz A, Granter SR, Mckee PH, Mihm MC. Amelanotic cellular blue nevus. A hypopigmented variant of the cellular blue nevus: Clinicopathologic análisis of 20 cases. Am J Surg Pathol 2002;26:1493-1500.

  7. Bolognia JL, Glusac EJ. Hypopigmented common blue nevi. Arch Dermatol 1998;134:754-6.

  8. Markus BF, Rüdiger H, Johannes R. A painless nodule on the dorsum of the foot. Arch Dermatol 2002;138:1091-6.

  9. Harris GR, Shea CR, Horenstein MG, Reed JA, Burchette JL, Prieto VG. Desmoplasic (Sclerotic) Nevus. An underrrecognized entity that resembles Dermatofibroma and Desmoplastic Melanoma. Am J Surg Pathol 1999;23:786-94.




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C?MO CITAR (Vancouver)

Med Cutan Iber Lat Am. 2006;34