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2019, Number 2

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Med Cutan Iber Lat Am 2019; 47 (2)

Sister Mary Joseph’s nodule. A case-series

González-Romero N, Aza-Martínez I, Cancho-Galán G, Gómez-Muga S, Urigoitia-Ugalde P, Izu-Belloso R
Full text How to cite this article

Language: Spanish
References: 9
Page: 139-143
PDF size: 328.18 Kb.


Key words:

Sister Mary Joseph’s nodule, cutaneous metastasis, umbilical nodule.

ABSTRACT

Sister Mary Joseph’s nodule (SMJN) is one of the differential diagnosis (DD) of an umbilical tumor. We present four cases of umbilical tumors. The first case is an 86-year-old woman with SMJN as a finding of an ovarian cancer. The second case, a 58-year-old male with anorexia, asthenia, and a SMJN as a finding of a signet-ring cell adenocarcinoma. The third case is a 79-year-old woman with an umbilical metastasis of an adenocarcinoma. Finally, a 60-year-old male operated for an umbilical hernia with two small erythematous nodules whose histological examination confirmed that it was a foreign body granuloma, SMJN-like. SMJN is an infrequent metastatic umbilical lesion secondary to a primary advanced intra-abdominal/intrapelvic malignancy. DD includes benign primary umbilical neoplasia (angioma, keloid), malignant primary neoplasm (basal cell epithelioma, etcetera) or other non-neoplastic lesion. The diagnosis is confirmed by a histological study. The most commonly related neoplasms are gastric or gynecological. SMJN is an ominous sign and the treatment is usually palliative. The role of the dermatologist is essential for the diagnosis of SMJN.


REFERENCES

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  2. Palaniappan M, Jose WM, Mehta A, Kumar K, Pavithran K. Umbilical metastasis: a case series of four Sister Joseph nodules malignancies. Curr Oncol. 2010; 17 (6): 78-81.

  3. Abu-Hilal M, Newman JS. Sister Mary Joseph and her nodule: historical and clinical perspective. Am J Med Sci. 2009; 337 (4): 271-273.

  4. Poparic S, Prohic A, Kuskunovic-Vlahovljak S, Guso E, Kapetanovic A. Sister Mary Joseph in an ovary adenocarcinoma. Med Arch. 2017; 71 (2): 154-157.

  5. Chalya PL, Mabula JB, Rambau PF, Mchembe MD. Sister Mary Joseph’s nodule at a university teaching hospital in northwestern Tanzania: a retrospective review of 34 cases. World J Surg Oncol. 2013; 5 (11): 151.

  6. Hussain DI, Ahmed KM, Hussain DS, Ahmed KF. Sister Mary Joseph nodule. A case report with review of literature. J Res Med Sci. 2009; 14 (6): 385-387.

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  9. Coll DM, Meyer JM, Mader M, Smith RC. Imaging appearances of Sister Mary Joseph nodule. Br J Radiol. 1999; 72 (864): 1230-1233.




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Med Cutan Iber Lat Am. 2019;47