Díaz‑Alfaro L, Organista A, Morales HD, Rodríguez‑Pulido JI, Solano VG

Language: Spanish
References: 17
Page: 256--260
PDF size: 207.00 Kb.

ABSTRACT

Alanine aminotransferase (ALT) is a cytoplasmic enzyme, more specific for liver damage, which has been quantified in crevicular fluid, however there are few reports that saliva can be a useful tool for the measurement of this enzyme. The objective of the study is to identify the levels of the ALT enzyme in unstimulated saliva of healthy patients and patients with periodontitis, before and after the non-surgical periodontal treatment. Material and methods:24 patients with moderate to advanced generalized periodontitis (n = 16) and patients with healthy periodontium (n = 8) who attended the Periodontics Clinic of the Didactic Medical Unit of the Autonomous University of Aguascalientes where the experimental group underwent non-surgical periodontal treatment. Unstimulated saliva was collected before and after the periodontal treatment to evaluate the ALT levels, processing its reading with a semi-automatic analyzer for clinical chemistry.Results: In the experimental group, an ALT concentration of 52.47 ± 72.68 was found, decreasing to 14.95 ± 16.88 after periodontal therapy, unlike the control group with a mean of 4.488 ± 3.229, finding an average of 5.638 ± 5.935 after periodontal treatment. Conclusion: In patients who underwent non-surgical periodontal treatment, the concentration of ALT tends to decrease significantly, however the results shown were not statistically significant.

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