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2019, Number 4

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Acta Med 2019; 17 (4)

Clembuterol food poisoning, sub-diagnosed condition

Ezquerra OA, Bueno AGM, Torres GKS, Arias MR, Ramírez GJE
Full text How to cite this article

Language: Spanish
References: 6
Page: 406-408
PDF size: 158.13 Kb.


Key words:

Clenbuterol toxicity, hypokalemia, toxindrome, anxiety, food poising, antidoping.

ABSTRACT

Clenbuterol is a beta agonist with anabolic and lipolytic properties, is approved for use in humans as a bronchodilator and is currently used among athletes as a drug of abuse. Illegal use of clenbuterol in cattle feed causes outbreaks of intoxication due to the consumption of meat or viscera. The most frequent manifestations are tachycardia, anxiety, tremors, vertigo, palpitations, weakness, headache, nausea, myalgias, paraesthesia, hypokalemia and transient hyperglycemia. Management is to prevent the cardiovascular and metabolic consequences, with the replacement of electrolytes. We present the case of two patients, who came in less than a month with adrenergic symptomatology, due to clenbuterol intoxication after the ingestion of beef liver, the predominant symptoms were tachycardia, hypertension, tremor and anxiety.


REFERENCES

  1. Hoffman RJ, Hoffman RS, Freyberg CL, Poppenga RH, Nelson LS. Clenbuterol ingestion causing prolonged tachycardia, hypokalemia, and hypophosphatemia with confirmation by quantitative levels. J Toxicol Clin Toxicol. 2001; 39 (4): 339-344.

  2. Secretaría de Salud Dirección General de Epidemiología México. Manual de procedimientos estandarizados para la vigilancia epidemiológica de la intoxicación alimentaria asociada al consumo de carne contaminada por clembuterol. 2012.

  3. Chai J, Xu Q, Dai J, Liu R. Investigation on potential enzyme toxicity of clenbuterol to trypsin. Spectrochim Acta A Mol Biomol Spectrosc. 2013; 105: 200-206.

  4. Brett J, Dawson AH, Brown JA. Clenbuterol toxicity: a NSW poisons information centre experience. Med J Aust. 2014; 200 (4): 219-221.

  5. Vulić A, Durgo K, Pleadin J, Herceg L, Kopjar N. Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro. Food Chem Toxicol. 2015; 77: 82-92.

  6. Bradberry S. Specific substances. Medicine. 2016; 44 (3): 127.




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Acta Med. 2019;17