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2019, Number 2

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Mediciego 2019; 25 (2)

Synovial sarcoma with medullary invasion

Dornes-Ramón R, Vázquez-Mora Y, Abreu-Figueredo N

Language: Spanish
References: 10
Page: 1-9
PDF size: 820.75 Kb.


ABSTRACT

Introduction: synovial sarcoma is a malignant neoplasm of mesenchymal origin, composed of spindle cells and a component of epithelial differentiation with varying degrees of dysplasia. It mainly affects the extremities, with predominance of the lower ones. Of the soft tissue sarcomas 5-10 % are synovial.
Objective: to present the case of a patient with synovial sarcoma from the imaging findings that made it possible to diagnose the disease.
Case presentation: female patient, 38 years old, with health history. She presented a painful picture in the distal region of the thigh, of 12 months of evolution, with increased volume and aggravation of symptoms in the last five months. Physical examination revealed changes in the texture of the skin of the right knee, moderate volume increase, and pain on palpation more pronounced in the distal region of the thigh, with limited movement. Nuclear magnetic resonance of the right thigh with intravenous contrast showed an extensive mass of heterogeneous appearance, enhanced with the administration of contrast medium (Dotarem) located predominantly in the distal third of the thigh, which invaded the medullary canal, associated with osteolysis and periostitis.
Conclusions: in the cases of patients with symptoms such as the one presented, the pertinent imaging studies should be carried out to confirm the diagnostic possibility of synovial sarcoma. Due to its characteristics, nuclear magnetic resonance is the imaging technique of choice to detect, characterize, stage and follow the evolution of these tumors.


REFERENCES

  1. García-Morato J, Damonte A, Rossetti NS, Arribalzaga EB. Evolución infrecuente de sinoviosarcoma de muslo. Rev Chil Cir [Internet]. Oct 2015 [citado 27 Jun 2016];67(5):527-30. Disponible en: http://www.scielo.cl/pdf/rchcir/v67n5/art11.pdf

  2. Pérez MA. Sarcoma de partes blandas del adulto. Experiencia Instituto de Oncología Dr. Luis Razetti. Rev Venez Oncol [Internet]. 2013 [citado 2 Ago 2016];25(3):166-77.Disponible en: http://www.redalyc.org/pdf/3756/375634879005.pdf

  3. Martínez-Ros J. Resultado del tratamiento del sarcoma sinovial en un centro de 3º nivel [Internet]. Murcia: Universidad de Murcia; 2015 [citado 22 Ene 2017]. Disponible en: https://www.tdx.cat/bitstream/handle/10803/310784/TJMR.pdf?sequence=1&isAllowed=y

  4. Serrano-García C. Estudio de vías de señalización en sarcomas [Internet]. Barcelona: Universidad Autónoma de Barcelona; 2014 [citado 10 Ene 2017]. Disponible en: http://ddd.uab.cat/pub/tesis/2014/hdl_10803_285748/csg1de1.pdf

  5. Corti-Hart MF, Nieto-González AM, Colina-Sánchez RE, Romano-Flores L, Milano-Molina M, Stock F. Sarcoma sinovial en adolescente. Presentación de un caso y revisión de la literatura. CIMEL [Internet]. 2011 [citado 27 Jul 2015];16(1):44-7. Disponible en: http://www.redalyc.org/pdf/717/71723602010.pdf

  6. Shuibat AM, Mamadova U, Yilmaz B, Alpaslan C, Ataç M, Gültekin SE. Synovial sarcoma, report of two cases in the mandible and infratemporal fossa. Oral Oncol [Internet]. May 2013 [citado 2 Ago 2016];49 Supl 1:S124. Disponible en: https://www.clinicalkey.es/service/content/pdf/watermarked/1- s2.0-S1368837513004089.pdf?locale=es_ES

  7. Leite de Alencar MH, Boldrini D, De Mendonça-Costa A, Talvane-Torres de Oliveira A, Sanches Attab C. Sarcoma sinovial primário do esôfago. Rev Col Bras Cir [Internet]. Oct 2012 [citado 11 Dic 2016];39(5):441-3. Disponible en: http://www.scielo.br/pdf/rcbc/v39n5/18.pdf

  8. Soria-Céspedes D, Galván-Linares AI, Oros-Ovalle C, Gaitan-Gaona F, Ortiz-Hidalgo C. Primary monophasic synovial sarcoma of the tonsil: immunohistochemical and molecular study of a case and review of the literature. Head Neck Pathol [Internet]. Dic 2013 [citado 27 Jul 2015];7(4):400-3. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824801/pdf/12105_2013_Article_440.pdf

  9. Stanelle EJ, Christison-Lagay ER, Healey JH, Singer S, Meyers PA, La Quaglia MP. Pediatric and adolescent synovial sarcoma: multivariate analysis of prognostic factors and survival outcomes. Ann Surg Oncol. Ene 2013;20(1):73-9.

  10. Silverstein D, Klein P. Large monophasic synovial sarcoma: a case report and review of the literature. Cutis [Internet]. Ene 2014 [citado 11 Dic 2016];93(1):13-6. Disponible en: https://mdedgefiles- live.s3.us-east-2.amazonaws.com/files/s3fs-public/Document/September-2017/CT093010013.pdf




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