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2006, Number 4

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Med Cutan Iber Lat Am 2006; 34 (4)

Treatment of plaque-type psoriasis with furfuril sorbitol

Martín-Ezquerra G, Sánchez-Regaña M, Umbert-Millet P
Full text How to cite this article

Language: Spanish
References: 6
Page: 155-158
PDF size: 198.27 Kb.


Key words:

psoriasis, anti-infl ammatory, furfuril sorbitol.

ABSTRACT

The topical treatment of psoriasis is sometimes diffi cult due to the intolerance and secondary effects of the classic options. The present study was undertaken to confi rm the effi cacy of a topical preparation containing furfuril sorbitol, a substance with anti-infl ammatory and antioxidant properties, for the maintaining treatment of plaque-type psoriasis.
Methods. Thirty patients with light or moderate plaque-type psoriasis were included in this blinded randomized and controlled with placebo study, with a 60 days follow-up. The cream was applied twice a day.
Results. A statistically signifi cative reduction of the PASI was shown, in relation to the placebo group, in the fourth and eighth week of treatment. The general evaluation of the effectivity of the treatment was positive, also signifi cative in relation to the placebo group. Nevertheless, no differences were found in the erythema, pruritus, desquamation nor infi ltration of the plaques. Tolerability was excellent.
Conclusions. The preparation containing furfuril sorbitol can be used as a maintaining complementary treatment in patents with plaque-type psoriasis.


REFERENCES

  1. Ferrándiz C, Bordas X, García-Patos V et al. Prevalence of psoriasis in Spain (Epiderma Project: phase I). JEADV 2001;15:20-3.

  2. Vena GA, Cassano N, Mastrolonardo M, Loconsole F, Coviello C, Arpaia N. Management of some inf lammatory dermatoses with a cosmetic preparation containing antioxidant /antiinflammatory agent. G Ital Dermatol 1998;133:373-80.

  3. G.A. Vena et al. Trattamiento della deramatite seborreica con una crema contenente furalglucitolo. An Ital Dermatol Clinic Sperim 1996;50:3-5.

  4. Fortuño Y, Kruger M, Macaya A, Peyrí J. Tratamiento de la cara roja con un preparado que contiene furfurilglucitol. Actas Dermosifi logr 2002;93:63-6.

  5. Artigas R, Revuelta J, Molina X. Efectividad de furlglucitol en el tratamiento de la dermatitis atópica. Dermatol Cosmet 2001;11:64-7.

  6. Coviello C, Vena G, Foti C, Grandolfo M, Angelini G. Trttamento del lupus eritematoso cutaneo e di alcune fotodermatosi croniche con una crema contenente furalglucitolo. An Ital Dermatol Clinic Sperim 1995;49: 117-21.




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C?MO CITAR (Vancouver)

Med Cutan Iber Lat Am. 2006;34