2018, Number 3
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ABSTRACTObjective: to characterize the use of antibiotics in patients with human immunodeficiency virus infection hospitalized at the “Pedro Kourí” Institute in the period from September to December 2016.
Material and Method: cross-sectional study with analytical component. The universe consisted of the 99 patients admitted to the hospital of the Pedro Kourí Institute (IPK) in the period from September to December 2016 with infection by the human immunodeficiency virus who was administered systemic antibiotic therapy for more than 48 hours.
Results: inappropriate use of antimicrobials was identified in 40.4% of patients. The main inappropriate indications were not to comply with hospital protocols (37.5%) and the use of antibiotics with unnecessarily broad spectrum (37.5%). This was most evident in bacterial pneumonia of patients with antibiotic misuse (40.4%). A significant association was found between the misuse of antibiotics and prolonged hospital stays, as well as between advanced immunosuppression and inappropriate use of these drugs.
Conclusions: inappropriate use of antimicrobials is common in patients with acquired immunodeficiency virus, particularly in bacterial pneumonias. This seems to be favored by the condition of the immunocompromised, violating the adjustment to established hospital protocols. Poor use of antimicrobials in turn affects the prolongation of hospital stays.
Dellit TH, Owens RC, McGowan Jr JE, Gerding DN, Weinstein RA, Burke JP, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship. Clinical Infectious Diseases. 2007;44:159-77.
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