2019, Number 4
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Otorrinolaringología 2019; 64 (4)
Sclerotherapy with bleomycin in the treatment of microcystic lymphatic malformation
Echeagaray-Sánchez HL, Del Bosque-Méndez JE, Soto-Becerril OA, Hernández-Abarca E, Gómez-De la Cruz CA
Language: Spanish
References: 11
Page: 229-233
PDF size: 486.58 Kb.
ABSTRACT
Background: Lymphatic malformations are developmental anomalies consisting of
abnormally formed lymphatic vessels; 50% of these lesions are diagnosed at birth, more
than 60% affect head and neck region, most frequently in oral cavity (75%) and the oral
tongue is the predominant subsite. The primary treatment for lymphatic malformations
is surgical excision. Some literature recommends sclerotherapy as first-line treatment for
lymphatic malformations, because of acceptable results and less comorbidities when
compared to surgical excision which carries higher complication rate associated with
extension, age of the patient and relation with vital structures.
Clinical case: A 37-year-old female patient, who referred increased volume in one
third anterior of oral tongue since birth. With pathological anatomy study at two months
of life it was diagnosed lymphangioma. At age of 34 years, patient refused surgical
treatment, thus, sclerotherapy with bleomycin was proposed, with which obtained a
good response.
Conclusions: Intralesional bleomycin is a safe and effective treatment of lymphatic
malformations showing acceptable results.
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