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ISSN 1726-6718 (Electronic)
Revista Cubana de Anestesiología y Reanimación

2019, Number 1

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Revista Cubana de Anestesiología y Reanimación 2019; 18 (1)

Effectiveness of three doses of succinylcholine in rapid sequence induction

Moreno LD, Cordero EI, Mora DI

Language: Spanish
References: 27
Page: 1-13
PDF size: 273.55 Kb.


ABSTRACT

Introduction: Rapid sequence intubation is a procedure that minimizes the time required to guarantee the respiratory airway in patients with high risk of bronchoaspiration.
Objectives: To compare the quality of intubation with three doses of succinylcholine in rapid sequence induction in patients with full stomach, as well as the side effects of such drugs.
Methods: An observational, cross-sectional study was carried out to assess the quality of intubation with rapid sequence intubation in emergency patients and with full stomach. The group I was administered 0.4 mg/kg of succinylcholine; the group II, 0.6 mg/kg; and the group III 1 mg/kg. The respiratory airway was assessed in all patients. The study was carried out in Hermanos Ameijeiras Clinical Surgical Hospital, between August 2013 and 2016.
Results: The time of visualization of the vocal folds was fast in the three groups. The best results were obtained in the group III, followed by the group II. The intubation conditions were excellent in the group III (90%), good in the group II (80%), and fair in the group I (70%). The hemodynamic variables showed significant differences among the three groups (p=0.008).
Conclusions: The effectiveness was determined of using three doses of succinylcholine in rapid sequence intubation, with optimal and safe intubation when succinylcholine was used at doses of 1 mg/kg, but it had a higher percentage of hemodynamic alterations as adverse effects.


REFERENCES

  1. Gómez Buitrago LM, Jaramillo J, Osorio López J, Reyes Duque G, Salcedo Briceño EE. Guía de práctica clínica: manejo de la vía aérea del paciente pediátrico con estómago lleno I parte. Rev Col Anest. 2007;35(2):101-20.

  2. Prakash S, Bardes Thakur P, Raj Logia A, Singh R. Intubating conditions following rapid sequence induction with three doses of succinylcholine. Indian J Anaesth. 2012;56(2):139-44.

  3. Ehrenfeld JM, Cassedy EA, Forbes VE, Mercaldo ND, Sandberg WS. Modified rapid sequence induction and intubation: a survey of United States current practice. Anesth & Analg. 2012;115(4):95-101.

  4. Sluga M, Ummenhofer W, Studer W, Siegemund M, Marsch SC. Rocuronium versus succinylcholine for rapid sequence induction of anesthesia and endotracheal intubation: A prospective, randomized trial in emergent cases. Anesth & Analg. 2005;101(5):1356-61.

  5. Grünberg G, Bounous A, Prestes I, Amonte G, Illescas L, Ferreira E, et al. Evaluación de los métodos predictores de vía aérea dificultosa en pacientes coordinados para procedimientos endoscópicos de vía aérea superior. Anest Analg Reanim. 2006;21(1):11-19.

  6. El-Orbany M, Connolly LA. Rapid sequence induction and intubation: current controversy. Anesth & Analg. 2010;110(1):318-25.

  7. Mechlin MW, Hurford WE. Emergency tracheal intubation: techniques and outcomes. Respir Care. 2014(6);59:881-92.

  8. Jensen AG, Callesen T, Hagemo JS, Hreinsson K, Lund V, Nordmark J. Scandinavian clinical practice guidelines on general anaesthesia for emergency situations. Acta Anaesthesiol Scand. 2010;54(8):922-50.

  9. Butler J, Sen A. Best evidence topic report. Cricoid pressure in emergency rapid sequence induction. Emerg Med J. 2005;22(11):815-6.

  10. Priebe HJ. Cricoid pressure: an expert’s opinion. Minerva Anestesiol. 2009;75(12):710-4.

  11. Almarales JR, Saavedra MA, Óscar Salcedo, Wady RD, Morales JF, Quijano CA, et al. Inducción de secuencia rápida para intubación orotraqueal en Urgencias. Rev Repertorio de Medicina y Cirugía. 2016;25(4):201-62.

  12. Cordero Escobar I. Los relajantes musculares en la práctica anestesiológica. Ciudad Habana: ECIMED; 2010 [20/04/2012] Disponible en: http://www.bvs.sld.cu/libros/relajante_muscular/indice_p.htm

  13. Naguib M, Samarkandi AH, El-Din ME, Abdullah K, Khaled M, Alharby SW. The dose of succinylcholine required for excellent endotracheal intubating conditions. Anesth & Analg. 2006;102(6):151-5.

  14. Pérez-Moreno A, Rodríguez MA, González MA, Sánchez-Elduayen MT. Dosificación actual de la succinilcolina. Rev Esp Anestesiol Reanim. 2007 [citado 25/01/2018]. Disponible en: https://www.sedar.es/images/stories/documentos/fondosredar/volumen54/.../cartdir.pdf

  15. Calvey TN, Williams NE. Drugs that act on the neuromuscular junction. In: Calvey N, Williams N, editors. Principles and practice of pharmacology for anaesthetists. 5th ed. New York: Blackwell Publishing; 2008. p. 178-82.

  16. Kopman AF, Lien CA, Naguib M. Determining the potency of neuromuscular blockers: are traditional methods flawed? Br J Anaesth. 2010;104(6):705-10.

  17. Ninan S, Jeslin L, Saravanan PA, Kumar K. Succinylcholine relaxant: Anaesthesiologist not relaxed. Indian J Anaesth. 2010;54(1):71-72.

  18. Blanié A, Ract C, Leblanc PE, Cheisson E, Huet O, Laplace C, et al. The limits of succinylcholine for critically III patients. Anesth & Analg. 2012;115(4):873-79.

  19. Maluenda BF, Aguilera FP, Kripper MC, Navea CO, Basaure VC, Saldías PF. Secuencia rápida de intubación en un Servicio de Urgencia. Rev Chilena de Med Intens. 2015;30(1):23-32.

  20. Dávila Cabo de Villa E, López González R, Márquez Ercia F, Hernández Dávila CM. Intubación de secuencia rápida. Medisur. 2015 [citado 04/10/2016];13(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1727-897X2015000400010

  21. Pérez Perilla P, Moreno Carrillo A, Gempeler Rueda FE. Guía para la secuencia de inducción e intubación rápida en el servicio de emergencias. Rev Univ Med. Bogotá. 2013;54(2):175-98.

  22. Bueno do Prado Guirro U, Romáo Martins R, Munechika M. Evaluación de la técnica de inducción en secuencia rápida de los anestesiólogos de un hospital universitario. Rev Bras Anestesiol. 2012;62(3):335-45.

  23. Rincón D, Navarro JR. Entubación con inducción de secuencia rápida: Recomendaciones para el manejo de la vía aérea. Rev Col Anest. 2004;32(2):89-98.

  24. Morgan GE. Manejo de la vía aérea. En: Morgan E. Anestesiología Clínica. 3ra. ed. México, DF: Editorial Moderno; 2003: pp. 65-90.

  25. EL-Orbany M, Connolly LA. Rapid sequence induction and intubation: current controversy. Anesth & Analg. 2010;110(5)1318-25.

  26. Hartley EL, Alcock R. Rocuronium Versus Suxamethonium: A Survey of First-line Muscle Relaxant Use in UK Prehospital Rapid Sequence Induction. Prehosp Disaster Med. 2015;30(2):184-6.

  27. Sajayan A, Wicker J, Ungureanu N, Mendonca C, Kimani PK. Current practice of rapid sequence induction of anaesthesia in the UK-a national survey. Br J Anaesth. 2016 [citado 05/09/2016];117:69-74. Disponible en: http://bja.oxfordjournals.org/content/117/suppl_1/i69.abstract?etoc




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