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Revista Cubana de Anestesiología y Reanimación

ISSN 1726-6718 (Electronic)
Revista Cubana de Anestesiología y Reanimación
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2019, Number 3

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Revista Cubana de Anestesiología y Reanimación 2019; 18 (3)

Perioperative benefits of distant ischemic conditioning in coronary revascularization

Hernández OR, Agüero MMO, González AO, Cordero EMI, Tamargo BTO
Full text How to cite this article

Language: Spanish
References: 13
Page: 1-15
PDF size: 291.48 Kb.


Key words:

distant ischemic conditioning, ischemia/reperfusion, coronary revascularization, enzymatic parameters, cardiac protection.

ABSTRACT

Introduction: A series of brief distant ischemia periods can limit myocardial damage produced by ischemia or reperfusion.
Objective: To analyze the differences between the two groups (control and study) taking into account the consumption of inotropics and/or vasopressors during the intraoperative and postoperative periods, as well as the incidence of major cardiac adverse events and mortality in the postoperative period.
Methods: A quasiexperimental, explanatory and comparative study with historical control was conducted on two groups of 247 patients proposed for coronary revascularization. A tourniquet was placed to the right arm, in the study group, alternating three insufflations with three dessufflations with a pressure of 200 mmHg, keeping each for five minutes. This procedure was performed before, during and after the major ischemic event, caused by pinching of the coronary artery.
Results: A significant decrease in the consumption of inotropic and vasoactive drugs was achieved. The decrease in the incidence of low reversible cardiac output, ventricular fibrillation, and new acute myocardial infarction was also proven.
Conclusions: Distant ischemic conditioning is an important tool to be taken into account for perioperative cardiac protection in coronary revascularization.


REFERENCES

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Revista Cubana de Anestesiología y Reanimación. 2019;18