2019, Number 5
<< Back Next >>
Rev Mex Pediatr 2019; 86 (5)
Incidence of acute renal injury in prematures under 1500 grams in a Neonatal Colombian Unit
Vásquez‑Hoyos P, González‑Clavijo T, Méndez‑García DP, Monje‑Cardona I, Saavedra‑Soler N
Language: Spanish
References: 15
Page: 181-184
PDF size: 245.65 Kb.
ABSTRACT
Introduction: There are few studies on acute kidney injury (AKI) in preterm infants; currently, there are no criteria for its definition and management.
Objective: To determine the incidence of AKI in preterm infants hospitalized in a neonatal care unit (NICU).
Material and methods: Descriptive cohort study of newborns weighing ≤ 1,500 grams admitted to the NICU of a university hospital in Bogotá, over a period of one year. All the patients were sampled serum creatinine at 24 and 72 hours of life. ARI was defined as an increase of creatinine ≥ 0.3 mg/mL or increased 150% of the initial value.
Results: 53 patients were included. Eleven patients were excluded because they died before 72 hours after birth. Ten patients met the definition of ARI and correspond to an incidence of 23.8% (95% CI 11.7 to 34.6%). There were three cases that also presented oliguria.
Conclusions: Our definition shows a high incidence of AKI in premature newborns. More studies are needed to confirm these findings and establish risk factors associated with AKI.
REFERENCES
Chua AN, Sarwal MM. Acute renal failure management in the neonate. NeoReviews. 2005; 6(8): e369-e376.
Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007; 11(2): R31.
Stojanović V, Barišić N, Milanović B, Doronjski A. Acute kidney injury in preterm infants admitted to a neonatal intensive care unit. Pediatr Nephrol. 2014; 29(11): 2213-2220.
Askenazi D, Saeidi B, Koralkar R, Ambalavanan N, Griffin RL. Acute changes in fluid status affect the incidence, associative clinical outcomes, and urine biomarker performance in premature infants with acute kidney injury. Pediatr Nephrol. 2016; 31(5): 843-851.
Chan JC, Williams DM, Roth KS. Kidney failure in infants and children. Pediatr Rev. 2002; 23(2): 47-60.
Daga A, Dapaah-Siakwan F, Rajbhandari S, Arevalo C, Salvador A. Diagnosis and risk factors of acute kidney injury in very low birth weight infants. Pediatr Neonatol. 2016.
Drukker A, Guignard JP. Renal aspects of the term and preterm infant: a selective update. Curr Opin Pediatr. 2002; 14(2): 175-182.
Kelly LK, Seri I. Renal developmental physiology: relevance to clinical care. NeoReviews. 2008; 9(4): e150-e161.
Ringer SA. Acute renal failure in the neonate. NeoReviews. 2010; 11(5): e243-e251.
Nagaraj N, Berwal PK, Srinivas A, Berwal A. A study of acute kidney injury in hospitalized preterm neonates in NICU. J Neonatal Perinatal Med. 2016; 9(4): 417-421.
Askenazi D, Patil NR, Ambalavanan N, Balena-Borneman J, Lozano DJ, Ramani M et al. Acute kidney injury is associated with bronchopulmonary dysplasia/mortality in premature infants. Pediatr Nephrol. 2015; 30(9): 1511-1518.
Koralkar R, Ambalavanan N, Levitan EB, McGwin G, Goldstein S, Askenazi D. Acute kidney injury reduces survival in very low birth weight infants. Pediatr Res. 2011; 69(4): 354-358.
Kavaz A, Ozçakar ZB, Kendirli T, Oztürk BB, Ekim M, Yalçinkaya F. Acute kidney injury in a paediatric intensive care unit: comparison of the pRIFLE and AKIN criteria. Acta Paediatr. 2012; 101(3): e126-129.
Durkan AM, Alexander RT. Acute kidney injury post neonatal asphyxia. J Pediatr. 2011; 158(2 Suppl): e29-33.
Giapros VI, Andronikou SK, Cholevas VI, Papadopoulou ZL. Renal function and effect of aminoglycoside therapy during the first ten days of life. Pediatr Nephrol. 2003; 18(1): 46-52.