San Juan SL, Fernández LV, Puente MMJ, Elizalde Martínez-Peñuela CR

Language: Spanish
References: 8
Page: 1-8
PDF size: 273.10 Kb.

ABSTRACT

Disseminated peritoneal leiomyomatosis is a rare entity of uncertain etiology, characterized by the proliferation of multiple benign nodules in the peritoneal cavity. These nodules are formed by smooth muscle cells, which can simulate peritoneal carcinomatosis. It manifests predominantly in women of childbearing age, especially during pregnancy or with the use of oral contraceptives. We report here the case of a 40-year-old woman diagnosed with disseminated peritoneal leiomyomatosis, who underwent simple hysterectomy due to uterine myomatosis. Two years after the diagnosis, she presented with an exacerbation of the disease and malignancy was suspected. So exploratory laparotomy was performed. Multiple myomatous nodules were observed, extended by omentum, peritoneum and appendix. All nodules were removed -omentectomy, appendectomy and bilateral adnexectomy. Biopsy confirms the diagnosis of disseminated peritoneal leiomyomatosis. As of today, the patient remains asymptomatic after 6 years of follow-up.

REFERENCES

1. García M, Viciano V, Aguiló J, Torro J, Medrano J, Ferri RJ, et al. Leiomiomatosis peritoneal diseminada. A propósito de un caso y revisión bibliográfica. Cirugía Española. 2001;69:610-2.

2. Alonso-Pacheco L, Rodrigo-Olmedo M. Leiomiomatosis peritoneal. Caso tratado mediante laparoscopia. Ginecol Obstet Mex. 2014;82:350-3.

3. Halama N, Grauling-Halama SA, Daboul I. Familial clustering of leiomyomatosis peritonealis disseminata: An unknown genetic syndrome? BMC Gastroenterol. 2005;5:33.

4. Surmacki P, Sporny, Tosiak A, Lasota J. Disseminated peritoneal leiomyomatosis coexisting with leiomyoma of the uterine body. Arch Gynecol Obstet. 2006;273:301-3.

5. Nappi C, Di Spiezio Sardo A, Mandato VD, Bifulco G, Merello E, Savanelli A, et al. Leiomyomatosis peritonealis disseminata in association with Currarino sindrome? BMC Cancer. 2006;6:127.

6. Al-Talib A, Tulandi T. Pathophysiology and possible iatrogenic cause of leiomiomatosis peritonealis desseminata. Gynecol Obstet Invest. 2010;69:239-44.

7. Wu C, Zhang X, Tao X, Ding J, Hua K. Leiomyomatosis peritonealis disseminata: A case report and review of the literature. Mol Clin Oncol. 2016 Jun;4(6):957–8.

8. Angel-Cano G, Castro-Solís J, Arango-Martínez A. Leiomiomatosis parásita en Medellín, Colombia: Reporte de un caso y revisión de la literatura. Rev Colomb Ginecol. 2014;65:179-82.