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2019, Number 3

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Med Cutan Iber Lat Am 2019; 47 (3)

Chronic disseminated histoplasmosis with lesions in the genital area

Durán L, Troya J, Duprez A, Fontana I, Palmeyro C, Barbarulo A
Full text How to cite this article 10.35366/91765

DOI

DOI: 10.35366/91765
URL: https://dx.doi.org/10.35366/91765

Language: Portugu?s
References: 7
Page: 227-230
PDF size: 645.70 Kb.


Key words:

Histoplasmosis, genital ulcers, diabetes, itraconazole.

ABSTRACT

A 75-year-old male patient with a personal pathological history of type II Diabetes, who had genital lesions of years evolution: small ulcerations on an indurated base, with well-defined edges on the glans and preputial balano sulcus; at the base of the penis papular and verrucous lesions. Histopathology reported cutaneous histoplasmosis, with nodular images in the right lung and non-caseating granulomas in the liver. Chronic disseminated histoplasmosis occurs more frequently in men older than 56 years, the male/female ratio is 10:1, the predisposing factors are type II diabetes, alcoholism, smoking, and the use of immunosuppressive drugs for periods of time prolonged The prognosis varies with the different clinical forms; it is all the more serious, the more acute the evolution and the greater the commitment of immunity. We highlight the good response in our patient to treatment with Itraconazole.


REFERENCES

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  2. Negroni R. Histoplasmosis en América Latina. Biomédica Instituto Nacional de Salud, Vol. 31, No. 3, Bogotá, D.C., Colombia-Septiembre, 2011.

  3. Rodriguez N, Sandoval M, Alsina A, Vidal C, del Sordo M, Muro F et al. Histoplasmosis genital. Presentación de un caso clínico. Arch Esp Urol. 2003; 56 (5): 462-466.

  4. Paixão M, Amante MH, Avancini J, Belda W Jr. Primary cutaneous histoplasmosis developed in the penis of an immunocompetent patient. An Bras Dermatol. 2015; 90 (2): 255-257.

  5. Marini M, Starck F, Parra S, Remorino ML, Casas J, Finquelievich JL. Histoplasmosis genital. Un caso de difícil diagnóstico. Act Terap Dermatol. 2006; 29: 184.

  6. Chaurasia D, Agrawal R, Misra V, Bhargava A. Penoscrotal histoplasmosis following bladder carcinoma. Int J Urol. 2007; 14: 571-572.

  7. Chawla A, Chawla K, Thomas J. Genitourinary histoplasmosis in post-renal transplant patient: diagnostic dilema. Indian J Urol. 2012; 28: 359-361.




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Med Cutan Iber Lat Am. 2019;47