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2020, Number 1

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Acta Pediatr Mex 2020; 41 (1)

Hearing disorders in preterm neonates upon leaving a natal intensive care unit

Venegas-Andrade A, Tello-Valdés CA, Iglesias-Leboreiro J, Bernárdez-Zapata I, Cuevas-Rivas AP, Rodríguez-Sataolaya P, De Luna-Sánchez IG, Ortega-Cisneros CM

Language: Spanish
References: 27
Page: 1-10
PDF size: 227.13 Kb.


ABSTRACT

Objective: To estimate the frequency of hearing disorders of preterm infants upon leaving from the neonatal intensive care unit (NICU), as well as to identify the risk factors associated with these abnormalities.
Material and Methods: Retrospective cross-sectional study with pre-term infants born at the Hospital Español between 2014 and 2016. Sex, gestational age at birth, various neonatal pathologies and exposure to two ototoxic drugs were evaluated. All subjects were evaluated with ABRs within 72 hours prior leaving NICU. The risks were presented as odds ratio (OR).
Results: 364 neonates were included, with gestational age at birth of 34 weeks (median), 53% male and 47% female. They presented intrauterine growth restriction 12.9%, hyperbilirubinemia 49.7%, sepsis 31.0%, intraventricular hemorrhage 3.6%, perinaischemic hypoxic encephalopathy 1.4%, furosemide exposure 11.0% and aminoglycosides 64.6%. ABR abnormalities were as follows: increments of interpeak latency I-III 37.9%, III-V 4.4% and I-V 13.5%. Wave I latencies were prolonged in 6.6%, wave III in 1.9% and 10.4% of wave V.
Conclusions: In accordance to previous studies, we found that hyperbilirubinemia, sepsis, intraventricular hemorrhage and furosemide use in premature babies, increase the probability of auditory conduction abnormalities in interpeak latencies I-III, III-V and I-V. Intrauterine growth restriction was a protective factor in this sample.


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