2020, Number S1
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Rev Med Inst Mex Seguro Soc 2020; 58 (S1)
Relationship between BCG vaccination and increased mortality from COVID-19. An ecological fallacy?
Villasís-Keever MÁ, Miranda-Novales MG
Language: Spanish
References: 5
Page: 1-2
PDF size: 308.25 Kb.
ABSTRACT
Ecological studies are one of the most common
study designs used to establish the association
between certain factors and disease development.
However, they have limitations mainly on how to
measure the variables, so their results must be
verified in studies with greater validity. The possible
link between increased mortality from COVID-19
and non-vaccination by Bacillus Calmette-Guérin
(BCG) is in doubt, due to the lack of rigor in the
study methodology.
REFERENCES
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Moorlag SJCFM, Arts RJW, van Crevel R, Netea MG. Non-specific effects of BCG vaccine on viral infections. Clin Microbiol Infect. 2019;25(12):1473- 1478. DOI: 10.1016/j.cmi.2019.04.020 2
Washio M, Oura A, Mori M. Ecological studies on influenza infection and the effect of vaccination: their advantages and limitations. Vaccine. 2008;26(50): 6470-6472. DOI: 10.1016/j.vaccine.2008.06. 037
Neumark Y. What can ecological studies tell us about death? Isr J Health Policy Res. 2017;6(1):52. DOI: 10.1186/s13584-017-0176-x
Salkeld DJ, Antolin MF. Ecological Fallacy and Aggregated Data: A Case Study of Fried Chicken Restaurants, Obesity and Lyme Disease. Ecohealth. 2020;17(1):4-12. DOI: 10.1007/s10393-020-01472-1
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