2020, Number 1
Dermatología Cosmética, Médica y Quirúrgica 2020; 18 (1)
Clinical and Demographic Characteristics of Syphilis in a Tertiary-Care Hospital in Mexico
Cruz-Gómez LG, Cárdenas-de la Garza JA, de la Cruz-Valadez E, Cuéllar-Barboza A, Martínez-Moreno A, Áncer-Arellano J, García-Lozano JA, Ocampo-Candiani J, González-González SE
Language: Spanish
References: 10
Page: 8-12
PDF size: 148.50 Kb.
ABSTRACT
Background: syphilis incidence has increased in the last decades
and recent clinical information in Latin America is scarce.
Methods: we performed a retrospective, observational and
descriptive study of patients diagnosed with syphilis in a tertiary-
care hospital in Northeastern Mexico from January 2013
to December 2019. Information was retrospectively retrieved
from clinical files. Normality was tested by Shapiro-Wilk test.
Chi square and the Mann-Whitney U test were used to compare
variables with
p ‹ 0.05 deemed as statistically significant.
Results: the most frequent clinical presentation was secondary
syphilis followed by neurosyphilis and ocular syphilis. The most
frequent comorbidity was HIV infection.
Conclusion: syphilis should be considered as differential diagnosis
of patients with clinical manifestations involving the
skin, central nervous system, oral mucosa, and eyes. Intentional
clinical examination and interrogation helps recognize clues to
detect this reemerging infection.
REFERENCES
World Health Organization (who), Guidelines for the treatment of Treponema pallidum (syphilis)”, Ginebra, who, 2016. Disponible en: http://apps.who.int/iris/bitstream/handle/10665/249572/9789241 549806-eng.pdf;jsessionid=197DFAFF6A3DF3213347894A810C89AB? sequence=1.
Herrera-Ortiz A, Uribe-Salas FJ, Olamendi-Portugal ML, García-Cisneros S, Conde-González CJ y Sánchez-Alemán MA, Trend analysis of acquired syphilis in Mexico from 2003 to 2013, Salud Pública Mex 2015;57(4):335-42.
Dirección General de Epidemiología, Anuario de morbilidad 1984-2017, México, Secretaría de Salud, 2018. Disponible en: http://www.epidemiologia. salud.gob.mx/anuario/html/incidencia_casos.html.
Zhang X, Zhang T, Pei J, Liu Y, Li X y Medrano-Gracia P, Time series modelling of syphilis incidence in China from 2005 to 2012, plos one 2016;11(2):e0149401.
Nishal PK, Kapoor A, Jain VK, Dayal S y Aggarwal K, Changing trends in acquired syphilis at a tertiary care center of North India, Indian J Sex Transm Dis 2015;36(2):149-53.
Rowley D, Swie‚ cki P, Firlag-Burkacka E, Sabin C, Kümmerle T, Surah S et al., Clinical and epidemiological characteristics of patients with early syphilis from three academic centres in Poland, Germany and Ireland: initial findings from the poets study, Sex Transm Infect 2015; 91(6):389-94.
Azariah S, Is syphilis resurgent in New Zealand in the 21st century? A case series of infectious syphilis presenting to the Auckland Sexual Health Service, NZ Med J 2005;118(1211):U1349.
Gutierrez-Galhardo MC, Do Valle GF, Sá FC, Schubach Ade O y Do Valle AC, Clinical characteristics and evolution of syphilis in 24 hiv+ individuals in Rio de Janeiro, Brazil, Rev Inst Med Trop Sao Paulo 2005; 47(3):153-7.
Roberts CP y Klausner JD, Global challenges in human immunodeficiency virus and syphilis coinfection among men who have sex with men, Expert Rev Anti Infect Ther 2016;14(11):1037-46.
Chemtob D, Gandacu D, Mor Z, Grotto I, Anis E y Rosenberg E, A national strategic plan for reducing the burden of sexually transmitted infections in Israel by the year 2025, Isr J Health Policy Res 2017;6:23.
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