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Órgano Oficial de la Asociación Dental Mexicana

2020, Number 2

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Rev ADM 2020; 77 (2)

The long-term risks and complications of bovine-derived xenografts

Rodríguez ÁE, Nowzari H

Language: Spanish
References: 39
Page: 108-116
PDF size: 674.15 Kb.


ABSTRACT

The frequency of dental implant related surgeries that involve soft and bone augmentation procedures has increased significantly. Bovine-derived substitutes have been by far the most commonly used xenografts in dentistry. Albeit literature is replete with clinical studies in favor of bovine-derived graft materials, bibliographical data reporting on risks and clinical complications is scarce. Clinical impression and concern for patients’ safety led to the report we have provided. The aim of the present case series was to raise awareness on the long-term risks and late clinical complications of bovine-derived graft materials. Patients were referred to a private practice due to bone augmentation complications. Demographics, significant medical and dental findings are reported. The present report was conceived with the safety of patients in mind. Complications included sinus and maxillary bone pathoses, displacement of the graft materials, oro-antral and oro-nasal communications, paresthesia, implant failure, foreign body reactions, encapsulation, chronic inflammation, soft tissue fenestrations and associated cyst. Bovine-derived graft materials were not biodegradable. Resolution of the associated lesions and symptoms was achieved after the removal of the bone graft materials. Clinicians seeking to provide functional and esthetic outcomes should be aware of the complications of the bovine-derived graft materials. The long-term safety of xenografts and their potential association with disease are valid concerns.


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