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2020, Number 1

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Rev Mex Pediatr 2020; 87 (1)

Comparison of the effect of transfusion of red cell concentrate in blood oxygen content of infants without sepsis, with sepsis and septic shock

Díaz Caneja-Arenas R, Iglesias-Leboreiro J, Bernárdez-Zapata I, Orozco-Romero DP, Rendón-Macías ME

Language: Spanish
References: 18
Page: 7-12
PDF size: 256.25 Kb.


ABSTRACT

Transfusion of erythrocyte concentrate (EC) in critically ill neonates may be justified in the intention of increasing the arterial oxygen content (CaO2), it is possible that the serious condition modifies its effectiveness. Objective: To compare the change in post-transfusion CaO2 in neonates without sepsis, with sepsis and septic shock. Material and methods: 110 neonates in their first transfusion: 14 with septic shock, 38 with sepsis and 58 without sepsis. CaO2 was compared before and after the transfusion. With data obtained by arterial blood gas, CaO2 was established with the formula: (Hb * 1.34 * SatO2) + (pO2 * 0.003)]. Results: Post-transfusion hemoglobin levels increased, but differed between groups, being lower in septic shock: without sepsis 13.9 ± 1.2 g / dL, sepsis 14.1 ± 1.6 and septic shock 12.5 ± 2.4. The same was observed with CaO2 mL/dL: 18.2 ± 2.02, 17.3 ± 2.8 and 15.3 ± 3.6, respectively. Conclusion: Apparently, hemodynamic instability is related to a minor increase in CaO2 after EC transfusion. Further studies are required to verify these findings.


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