medigraphic.com
Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 05

<< Back Next >>

Ginecol Obstet Mex 2020; 88 (05)

Breast cancer survival at 5 years: Experience of an institution at Jalisco, México

Dorado-Roncancio EF, Vázquez-Nares JJ, Hernández-Garibay CA, García GIJ

Language: Spanish
References: 14
Page: 312-320
PDF size: 263.79 Kb.


ABSTRACT

Objective: To determine the 5-year survival (global and disease-free) after the treatment of patients with breast cancer at the Instituto Jalisciense de Cancerología.
Materials and Methods: Observational, descriptive cross-sectional, retrospective study of patients diagnosed with breast cancer treated during 2013 in the breast clinic service of the Instituto Jalisciense de Cancerología, Guadalajara. The five-year global and disease-free survival was established from the time elapsed from the diagnosis until the occurrence of an event (recurrence, metastasis or death) or date of last contact, with a limit to December 2018.
Results: 311 files were reviewed, but only 172 were included for the analysis of overall survival and disease-free survival at five years. The average age at diagnosis was 51.4 years. The most repeated stage was IIIA, determined in 64 patients (37.4%), IIA in 38 patients (22.2%), IIB in 19 patients (11.1%), AI and IIIC each with 15 patients (8.8%). The probability of five-year global survival was 78.5%. 24.4% presented recurrence with an average survival of 46.8 months. Statistical significance was demonstrated between stage, histological grade, result of immunohistochemistry and lymph node invasion and survival.
Conclusions: This research represents an effort to establish the five-year survival of our patients. In the population studied, survival had acceptable and comparable values with other national and international studies and reflects the good medical practice of our institution.


REFERENCES

  1. Global Cancer Observatory, Globocan 2018. https://gco. iarc.fr/today/data/factsheets/populations/900-world-factsheets. pdf. Y Mexico - Global Cancer Observatory https:// gco.iarc.fr/today/data/factsheets/populations/484-mexico- fact-sheets.pdf Revisado 28 noviembre, 2019

  2. Instituto Nacional de Estadísticas y Geografía, INEGI 2014. https://www.inegi.org.mx/contenidos/transparencia/ contenidos/doc/inf2014.pdf

  3. National Cancer Institute. Cancer of the Female Breast (Invasive). SEER Cancer Statistics Review 1975-2014. Updated April 2, 2018. https://seer.cancer.gov/archive/ csr/1975_2014/results_merged/sect_04_breast.pdf

  4. Berek Jonathan, Hacker Neville. Gynecologic Oncology. Wolters Kluwer. 6 th ed. 2015 http://1.droppdf.com/ files/gYHVb/berek-and-hackers-gynecologic-oncology-6e- 2015-pdf-unitedvrg-.pdf

  5. Sun YS, et al. Risk factors and preventions of breast cancer. Int J Biol Sci. 2017; 13 (11): 1387-97. doi: 10.7150/ ijbs.21635

  6. Nelson HD, et al. Risk factors for breast cancer for women age 40 to 49: A systematic review and meta-analysis. Ann Intern Med. 2012; 156 (9): 635-48. doi: 10.7326/0003- 4819-156-9-201205010-00006

  7. Kandil MA, et al. Study of prognostic and predictive factors in locally advanced breast cancer in Egypt. Menoufia Med 2018; 31: 339-47. doi: 10.4103/mmj.mmj_17_18

  8. Rodríguez-Cuevas S, et al. Breast carcinoma presents a decade earlier in Mexican women than in women in the United States or European countries. Cancer 2001; 91: 863-68. https://doi.org/10.1002/1097-0142(20010215) 91:4<863::AID-CNCR1074>3.0.CO;2-Y

  9. NIH. Cancer Stat Facts: Female Breast Cancer. http://seer. cancer.gov/statfacts/html/breast.html.

  10. Allemani C, et al. Breast cancer survival in the US and Europe: a CONCORD high-resolution study. Int J Cancer. 2013; 132 (5): 1170-8. https://doi.org/10.1002/ijc.27725

  11. Cancer Research UK. Breast cancer five-year net survival by stage, with incidence by stage (all data: adults diagnosed 2013-2017, followed up to 2018). https:// www.cancerresearchuk.org/health-professional/cancer- statistics/statistics-by-cancer-type/breast-cancer/ survival?_ga=2.45344162.784110726.1586130926- 1514958540.1586130926#heading-Three

  12. Perou C, et al. Molecular Portraits of Human Breast Tumors. Nature. 2000;406:747-52. doi: 10.1038/35021093

  13. Ries LG, et al. Chapter 13 - Cancer of the female breast. In: Ries LG, Young JL, Keel GE, Eisner MP, Lin YD, Horner M-J (editors). SEER Survival Monograph: Cancer survival among adults: US SEER Program, 1988-2001, patient and tumor characteristics. National Cancer Institute, SEER Program, NIH Pub. No. 07-6215, Bethesda, MD, 2007. https://seer.cancer.gov/archive/publications/survival/ seer_survival_mono_lowres.pdf

  14. Kim YY, et al. Prognostically distinctive subgroup in pathologic N3 breast cancer. J Breast Cancer. 2016; 19( 2): 163-68. doi: 10.4048/jbc.2016.19.2.163




2020     |     www.medigraphic.com