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ISSN 0210-5187 (Electronic)

2020, Number 1

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Med Cutan Iber Lat Am 2020; 48 (1)

Juvenile systemic sclerosis in an infant: case report

Romero FA, Chávez DN, Toro AM, Vivar MC

Language: Spanish
References: 9
Page: 69-74
PDF size: 327.82 Kb.


ABSTRACT

Juvenile systemic scleroderma is a rare chronic pathology of connective tissue, whose symptoms begin on average at age 11. It has a high morbidity and mortality, being a disease of which there is no consensus of treatment, so it becomes a challenge for the specialists who manage it. This paper describes a case of diffuse systemic juvenile cutaneous scleroderma in a one-year-old girl, diagnosed and treated in a multidisciplinary manner at the «Baca Ortiz» Children’s Hospital in Quito, Ecuador, which highlights the importance of maintaining a high level of suspicion, allowing early diagnosis, and carrying out pharmacological and non-pharmacological treatments to stabilize the activity of the disease and improve the quality of life of people affected by this disease.


REFERENCES

  1. Pope JE, Johnson SR. New classification criteria for systemic sclerosis (scleroderma). Rheum Dis Clin North Am. 2015; 41 (3): 383-398.

  2. Herrick AL, Ennis H, Bhushan M, Silman AJ, Baildam EM. Incidence of childhood linear scleroderma and systemic sclerosis in the UK and Ireland. Arthritis Care Res (Hoboken). 2010; 62 (2): 213-218.

  3. Agarwal SK, Tan FK, Arnett FC. Genetics and genomic studies in scleroderma (systemic sclerosis). Rheum Dis Clin North Am. 2008; 34 (1): 17-40; v.

  4. Salehzadeh F. A useful clinical sign in pediatric systemic sclerosis. J Clin Rheumatol. 2017; 23 (2): 113.

  5. Li SC. Scleroderma in children and adolescents: localized scleroderma and systemic sclerosis. Pediatr Clin North Am. 2018; 65 (4): 757-781. doi: 10.1016/j.pcl.2018.04.002.

  6. Zulian F, Balzarin M, Birolo C. Recent advances in the management of juvenile systemic sclerosis. Expert Rev Clin Immunol. 2017; 13 (4): 361-369. doi: 10.1080/1744666X.2017.1243467.

  7. Adrovic A, Şahin S, Barut K, Kasapçopur Ö. Juvenile scleroderma: a referral center experience. Arch Rheumatol. 2018; 33 (3): 344-351.

  8. Denton CP, Khanna D. Systemic sclerosis. Lancet. 2017; 390 (10103): 1685-1699. doi: 10.1016/S0140-6736(17)30933-9.

  9. Martini G, Vittadello F, Kasapçopur O, Magni-Manzoni S, Corona F, Duarte-Salazar C et al. Factors affecting survival in juvenile systemic sclerosis. Rheumatology (Oxford). 2009; 48 (2): 119-122.




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