García-Manzano RA, Carmona-Pavón ML, Dávila-Ruiz EO, Barker-Antonio A, García-Espinoza JA, Peñaloza-Ramírez R

Language: Spanish
References: 12
Page: 27-32
PDF size: 349.24 Kb.

ABSTRACT

Germ cell tumors are a condition found within differential diagnoses of anterior mediastinal masses. The symptomatology associated with these tumors is nonspecific but predominantly respiratory. Life-threatening complications include acute respiratory failure due to rupture of surrounding organs such as the lung (fistula), chest wall, and pericardium (tamponade). Because of these complications it is important to have a diagnostic suspicion especially in young women with related thoracic symptomatology. We present the case of a 41 year old female patient with respiratory symptomatology who in her study protocol is diagnosed as a tumor in the anterior and middle mediastinum, located towards the trunk of the pulmonary artery and left branch, bronchial arteries and left bronchus, left upper lobe to whom resection of the tumor is performed by medium sternotomy approach, with histopathological report of mature cystic teratoma with thymic tissue, mesenchymal cells, mature adipose tissue, intestinal epithelium, fragments of pancreas and mature cartilaginous tissue.

REFERENCES

1. Kharosekar HU, Naik H, Velho V. Mature cystic teratoma of dorsal spinal cord in adult: an unusual lesion. Asian J Neurosurg. 2018; 13(1): 140-143.

2. Medina M, Santana D, Beltrán MI, Serrano O. Síndrome de teratoma creciente: reporte de caso y revisión de la literatura. Rev Colomb Cancerol. 2015; 19(4): 244-248.

3. Gómez-Monterrosas O, Flores-García LE, Gómez-Garza G, Pichardo-Bahena R, Pantoja JP, Méndez-Sánchez N. Teratoma maduro de ovario como causa de abdomen agudo. Reporte de un caso. Med Sur. 2006; 13(4): 178-181.

4. Hakiri S, Kawaguchi K, Fukui T, Nakamura S, Ozeki N, Mori S, Goto M et al. Verification of the diagnostic strategy for anterior mediastinal tumors. Int J Clin Oncol. 2019; 24(4): 385-393.

5. Davis RD Jr, Oldham HN Jr, Sabiston DC Jr. Primary cysts and neoplasms of the mediastinum: recent changes in clinical presentation, methods of diagnosis, management, and results. Ann Thorac Surg. 1987; 44: 229-237.

6. Torres-Rodríguez T, Herrera-Cruz D, Gálvez-González M, Moran-Ocaña E, María del Cid-Herrera R, Gordillo-Castillo R. Masas mediastinales: epidemiología y decisiones estratégicas. Experiencia de 13 años. Neumol Cir Torax. 2016; 75(4): 268-274.

7. Hammen I, Lal Yadav A. Teratoma as unusual cause of chest pain, hemoptysis and dyspnea in a young patient. Respiratory Medicine Case Reports. 2018; 23: 77-79.

8. Lijima Y, Akiyama H, Nakajima Y, Kinoshita H, Hirata T. A case of primary mediastinal leiomyosarcoma in which long-term survival was achieved. Ann Thorac Cardiovasc Surg. 2018; 105(5): 1411-1418.

9. Di Lu, Siyang Feng, Xiguang Liu, Xiaoying Dong, Mei Li, Hua Wu et al. 3D-printing aided resection of intratracheal adenoid cystic carcinoma and mediastinal mature cystic teratoma in a 26-yearold female: a case report. J Thorac Dis. 2018; 10: E134-E137.

10. Ram D, Sharma DK, Darlong LM, Rajappa SK, Bhakuni YS. Mediastinal teratoma with pulmonary parenchyma fistula: a rare diagnostic endeavour. J Clin Diagn Res. 2017; (8): XD03-XD04.

11. Riegler J, Ebert A, Qin X, Shen Q, Wang M, Ameen M et al. Comparison of magnetic resonance imaging and serum biomarkers for detection of human pluripotent stem cell-derived teratomas. Stem Cell Reports. 2016; 6(2): 176-187.

12. Zhu T, Zhang X, Xu J, Tian J, Li H, Liu D et al. Endobronchial ultrasound guided-transbronchial needle aspiration vs. conventional transbronchial needle aspiration in the diagnosis of mediastinal masses: a meta-analysis. Mol Clin Oncol. 2014; 2(1): 151-155. Epub 2013 Oct 23.