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2020, Number S1

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Acta Pediatr Mex 2020; 41 (S1)

SARS-CoV-2 Virus. What is currently known?

Saltigeral-Simental P, León-Lara X

Language: Spanish
References: 24
Page: 3-7
PDF size: 874.11 Kb.


ABSTRACT

The SARS-CoV-2 was first identified in the city of Wuhan, China, in late 2019. Since then, the disease caused by this new coronavirus, COVID-19, represents a growing threat to human health. SARS-CoV-2 is an enveloped single-stranded RNA virus classified in the subfamily Coronavirinae, genus Betacoronavirus. The homology of genomes suggests that bats might be the original host of the virus, and pangolins the intermediate host. The viral glycoprotein S is a crucial target for the development of vaccines, therapeutic targets, and diagnostic tests. This protein facilitates viral entry into target cells and determines host tropism.


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