medigraphic.com
SPANISH

Revista Cubana de Oftalmología

ISSN 1561-3070 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2019, Number 4

<< Back Next >>

Rev Cub Oftal 2019; 32 (4)

Uveal melanoma of ciliary body

Garduño-Vieyra L, Ruiz-Quintero NC, de la Fuente-Batta I
Full text How to cite this article

Language: Spanish
References: 10
Page: 1-6
PDF size: 410.28 Kb.


Key words:

conjunctival melanoma, eye tumor, limbic nerve.

ABSTRACT

The objective of this case report is to describe the characteristics of a conjunctival bulging nevus in a 72-year-old female patient and the complementary tests that were performed to reach the diagnosis of conjunctival melanoma. Conjunctival melanoma is a rare tumor, which account for 2% of all eye tumors. The cells involved are the melanocytes of the conjunctival epithelium. A risk factor for this entity may be exposure to ultraviolet light. However, it has not been precisely described. Most cases originate from a primary acquired melanosis (50- 70%). The most common presentation is a pigmented, unilateral, elevated, thick, lesion with blood vessels and areas of melanosis around it. Its diagnosis is made with the clinical suspicion confirmed with the histopathological study. Current treatment is local excision, followed by cryotherapy, radiotherapy, or chemotherapy. Metastatic disease occurs in 11-42% and 20-52% of patients in a 5-year and 10-year follow-up, respectively.


REFERENCES

  1. Wong JR, Nanji AA, Galor A, Karp CL. Management of conjunctival malignant melanoma: a review and update. Expert Rev Ophthalmol. 2014;9(3):185-204.

  2. Vora FK, Demirci H, Marr B, Mruthyunjaya P. Advances in the management of conjunctival melanoma. Survey of Ophthalmology. 2017;62(1):26-42.

  3. Isager P, Engholm G, Overgaard J, Storm H. Uveal and Conjunctival Malignant Melanoma in Denmark 1943-97: Observed and Relative Survival of Patients Followed Through 2002. Ophthalmic Epidemiol. 2006;13(2):85-96.

  4. Chang AE, Karnell LH, Menck HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84 836 cases from the past decade. The American College Surgeons Comission on Cancer and the American Cancer Society. Cancer. 1998;83(8):1664-78.

  5. Brownstein S. Malignant melanoma of the conjunctiva. Cancer Control. 2004;11(5):310-6.

  6. Singh AD, Campos OE, Rhatigan RM, et al. Conjunctival melanoma in the black population. Surv Ophthalmol. 1998;43(2):127-33.

  7. Shields CL, Markowitz JS, Belinsky I, et al. Conjunctival Melanoma: Outcomes based on tumor origin in 382 consecutive cases. Ophthalmology. 2011;118(2):389-95.

  8. Shields JA, Shields CL, Mashayekhi A, et al. Primary acquired melanosis of the conjunctiva: Experience with 311 Eyes. Ophthalmol Soc. 2007;105:61.

  9. Kenawy N, Lake SL, Coupland SE, Damato BE. Conjunctival melanoma and melanocytic intraepitelial neoplasia. Eye. 2012;27(2):142-52.

  10. Fernandes BF, Nikolitch K, Coates J, et al. Local chemotherapeutic agents for the treatment of ocular malignancies. Surv Ophthalmol. 2014;59(1):97-114.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Cub Oftal. 2019;32