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Revista Mexicana de Trasplantes

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2020, Number S2

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Rev Mex Traspl 2020; 9 (S2)

COVID-19 in transplant recipients: comparison of severity between recipients and their relatives with close coexistence

Lerma-Sánchez V, Sánchez-Cárdenas M, Rodríguez-Armida M, Nava-Santana CA, del Toro-Cisneros N, Marino-Vazquez LA, Morales-Buenrostro LE
Full text How to cite this article 10.35366/94972

DOI

DOI: 10.35366/94972
URL: https://dx.doi.org/10.35366/94972

Language: Spanish
References: 13
Page: 238-242
PDF size: 220.91 Kb.


Key words:

Transplantation, immunosuppression, COVID-19, close coexistence.

ABSTRACT

Introduction: Due to their compromised immunity, transplant recipients could be expected to have an unfavorable clinical course after SARS-CoV-2 infection. On the other hand, it has been described that the viral load inhaled by each individual, the low socioeconomic level and even the HLA, could be correlated with the degree of severity of the clinical picture. This becomes relevant in the case of people with close contact as members of the same family who share a home. Objective: To compare the clinical evolution and outcomes of a group of kidney transplant recipients and their relatives, after COVID-19 infection. Methods: It is a comparative and retrospective study. Through the review of the electronic file and phone follow-up, clinical information was obtained of the evolution and outcome of couples infected simultaneously by COVID-19 (transplant recipient-close relative). Results: Data from nine pairs were captured. In four cases, the transplant recipient was older than their relative and in five cases the recipient had greater comorbidity. In relation to the severity of the condition, in six cases there were similar clinical evolution between the recipients and their relatives. There was one death in the group of family members, without deaths in the group of transplant recipients. Conclusions: We present a series of comparative cases with COVID-19, where despite greater comorbidity and immunosuppression, no worse prognosis was observed in the kidney transplant group.


REFERENCES

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Rev Mex Traspl. 2020;9