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2020, Number 4

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Rev ADM 2020; 77 (4)

Cleidocraneal dysostosis at three years of orthopedic treatment

Peralta-Dzib Á, Sansores-Ambrosio F, Loria-Mondragón T, Minaya-Sánchez M, Casanova-Rosado A, Casanova-Rosado J

Language: Spanish
References: 17
Page: 222-226
PDF size: 294.55 Kb.


ABSTRACT

Introduction: Cleidocranial dysostosis is a rare genetic disorder with a hereditary pattern. Its pathognomonic features are clavicular aplasia, fontanelles and open sutures, multiple dental anomalies. Its origin is related to alterations in the RUNX2 gene, important for the synthesis of CBFA1, which in turn functions as a bone conformer and an osteoblast differentiator. Clinical case: Patient with eleven years old with clinical characteristics of CCD, hereditary genetic background, and dental alterations related to cleidocranial dysostosis are corroborated. Result: After three years of treatment, the facial definition is better, the eruption of permanent pieces retained and better chewing function. Conclusion: Improve the quality of life of the patient with interceptive treatments and the knowledge of the alterations caused by the syndrome, as well as the interdisciplinary work.


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