2000, Number 4
Comparative study of the efficiency of acetic acid vs modified Dakin’s solution in the treatment of infections at the insitional site.
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ABSTRACTObjective: To assess the usefulness of acetic acid as cinoared to the modified Dakin’s solution in the treatment of infections at the insitional site.
Design: Controlled clinical assay.
Setting: Third level health care general hospital.
Patients and methods: Sixty patients with infected insitional site in the abdominal wall were included and assigned randomly to two groups. A) Patients treated with acetic acid solution and B) patients treated with the modified Dakin’s solution. We analysed the following data: Diagnosis, age, gender, required treatment time, time for negativization of the culture, results from the culture, colony forming unites per gram of tissue (CFU/g), and side effects.
Results: Both groups were similar in regard to age, gender distribution, diagnosis, and isolated germs. Bacteria obtained most frequently were Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. A significant different was found regarding healing time in favour of acetic acid (11.4 ± 3.04 days vs 13.6 ± 3.2 days for groups A and B, respectively, p = 0.002). The Pseudomonas infected lesions required less time to become negative in their cultures when treated with acetic acid (9 ± 1.7 vs 13.6 ± 2.1 days for Dakin’s solution; p = 0.0000). No side effects were observed in either group.
Conclusion: The use of acetic acid for the treatment of infections at the insitional site is efficient and safe. Acetic acid could the choice antiseptic for infections caused by Pseudomonas aeruginosa.
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