Chatterjee K, Gallo E

Language: English
References: 10
Page: 148-151
PDF size: 65.91 Kb.

ABSTRACT

Glicoprotein IIb/IIIa inhibitors are powerful platelet anti-aggregatory agents which have showed its great utility in the pharmacological management of patients undergoing acute coronary syndrome. Among the many related drugs currently used, a monoclonal antibody (abciximab), two non-peptidic GP IIa/IIIb receptor antagonists (Tirofiban and Lamifiban), and a peptidic antagonist (epitifibatide) all show, between them, important pharmacokinetics differences. Thus risk/benefit derived from its used should be considered based on each patient clinical profile.

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