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2020, Number 277

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16 de abril 2020; 59 (277)

Relation between COVID-19 and cardiovascular diseases

Fonseca MYI, Díaz RYL, Vargas FMÁ
Full text How to cite this article

Language: Spanish
References: 25
Page: 1-6
PDF size: 270.55 Kb.


Key words:

coronavirus, COVID-19, angiotensin II converting enzyme, cardiovascular system.

ABSTRACT

Introduction: SARS-CoV-2 severe acute respiratory syndrome, which is a new coronavirus identified as the cause of 2019 coronavirus disease (COVID-19), started in Wuhan, China in late 2019 and has spread throughout the world. Among the effects it produces are those produced at the cardiovascular system level, which are becoming increasingly relevant thanks to its impact on mortality. Objective: to describe the relationship between COVID-19 and cardiovascular diseases. Material and methods: a bibliographic review was carried out in the period from January to April 2020. The review covered high-impact Web of Science journals, national and international journals, mostly from studies conducted in China. The Pubmed, MEDLINE and Scielo databases were consulted using the terms “coronavirus”, “COVID-19”, “cardiovascular system”, “myocarditis”; for English and Spanish. 25 articles with adequate validity were selected. Development: myocardial damage is a frequent complication among the most severe patients with COVID-19, which seems related to the systemic inflammatory response, the effect of dysregulation of the angiotensin II converting enzyme, as well as of lung dysfunction itself and hypoxia. Cardiovascular diseases reported so far include: myocarditis, acute coronary syndrome, and congestive heart failure. Material and methods: a bibliographic review was carried out in the period from January to April 2020. The review covered high-impact Web of Science journals, national and international journals, mostly from studies conducted in China. The Pubmed, MEDLINE and Scielo databases were consulted using the terms “coronavirus”, “COVID-19”, “cardiovascular system”, “myocarditis”; for English and Spanish. 25 articles with adequate validity were selected. Development: myocardial damage is a frequent complication among the most severe patients with COVID-19, which seems related to the systemic inflammatory response, the effect of dysregulation of the angiotensin II converting enzyme, as well as of lung dysfunction itself and hypoxia. Cardiovascular diseases reported so far include: myocarditis, acute coronary syndrome, and congestive heart failure. Conclusions: COVID-19 has a great relationship with cardiovascular diseases, which corresponds to the pathophysiology of the disease and the body’s response to it.


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16 de abril. 2020;59