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2020, Number 3

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Universidad Médica Pinareña 2020; 16 (3)

Race against time: vaccine development for COVID-19

Saavedra-Camacho JL, Iglesias-Osores S
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Language: Spanish
References: 4
Page: 1-3
PDF size: 359.94 Kb.


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Mr. director:

For several months now, the global dynamics have changed due to a new disease, causing a severe acute respiratory syndrome by the coronavirus-2 (SARS CoV-2). COVID-19 pandemic has caused a global shock, inducing changes not only in the health field, but also in the social and political arena. It is crucial to develop safe and effective vaccines to control this disease, eliminate its spread and prevent future recurrence.
Ever since SARS CoV-2 shares significant sequence homology with two other coronaviruses (SARS-CoV and MERS-CoV) the vaccines identified in these patents related to those viruses could facilitate the design of vaccines against the virus causing COVID-19. There are 363 patents in the American Chemical Society (CAS) content collection related to the development of vaccines to prevent viral diseases, including SARS and MERS. Of these, 188 patents are directly associated with anti-SARS and anti-MERS vaccines with a demonstrated immune response.


REFERENCES

  1. Liu C, Zhou Q, Li Y, et al. Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases. ACS Cent Sci [Internet]. 2020 [citado 2020 Abr 27];6:315-331. Disponible en: http://dx.doi.org/10.1021/acscentsci.0c00272

  2. Amanat F, Krammer F. SARS-CoV-2 Vaccines : Status Report. Immunity [Internet]. 2020 [citado 2020 Abr 27]; 14;52(4):583–9. Disponible en: http://dx.doi.org/10.1016/j.immuni.2020.03.007

  3. Gretebeck LM, Subbarao K. Animal models for SARS and MERS coronaviruses. Curr Opin Virol [Internet]. 2015 [citado 2020 Abr 27]; 13:123-129. Disponible en: http://dx.doi.org/10.1016/j.coviro.2015.06.009

  4. Pang J, Wang MX, Ang IYH, et al. Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review. J Clin Med [Internet]. 2020 [citado 2020 Abr 27];9(623). Disponible en: http://dx.doi.org/10.3390/jcm9030623




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C?MO CITAR (Vancouver)

Universidad Médica Pinareña. 2020;16