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Revista Mexicana de Patología Clínica y Medicina de Laboratorio

ISSN 0185-6014 (Print)
Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio
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2020, Number 2

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Rev Mex Patol Clin Med Lab 2020; 67 (2)

Therapeutic plateletapheresis for the management of essential thrombocitosis, case report and review of the method

Guevara-Montero MA, Pérez‑Ong J, Vera-Delgado J, Saldierna-Jiménez E
Full text How to cite this article 10.35366/95551

DOI

DOI: 10.35366/95551
URL: https://dx.doi.org/10.35366/95551

Language: Spanish
References: 10
Page: 81-84
PDF size: 203.04 Kb.


Key words:

Therapeutic plateletapheresis, essential thrombocytosis, apheresis.

ABSTRACT

Introduction: A case of an 82-year-old male is reported, who comes to our center presenting an essential thrombocytosis, with platelet levels › 2,000 x 103/µL. The patient was treated by therapeutic plateletapheresis performed with a donation kit. At the end of the last procedure, he presented improvement. Objective: The parameters used in apheresis equipment are described. Material and methods: An Amicus® apheresis machine, a platelet donation kit, was used. Results: It was necessary to modify the parameters of the apheresis machine to enable it and thus achieve the procedure, since it was not designed to perform therapeutic plateletapheresis procedures, because it does not allow the introduction of pathological parameters. Two series of 6 procedures were performed, one every 24 hours. At the end of each series there was a decrease in platelet count and decrease in its symptomatology. Conclusions: After the series of procedures, clinical improvement (decrease in associated symptoms) and laboratory (a return in platelet numbers to normal ranges) were presented. This treatment should be considered as a good alternative in sites that do not have specific equipment for the performance of therapeutic plateletapheresis.


REFERENCES

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Rev Mex Patol Clin Med Lab. 2020;67