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Latinoamericana de lnfectología Pediátrica.
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Infectología Pediátrica, A.C.
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de lnfectología

2020, Number 3

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Rev Latin Infect Pediatr 2020; 33 (3)

Punta Toro virus: a Phlebovirus circulating in America

Zúñiga CIR, Lozano JC

Language: Spanish
References: 8
Page: 122-124
PDF size: 139.43 Kb.


ABSTRACT

Punta Toro Virus (genus Phlebovirus, family Bunyaviridae), a member of the sandfly fever group, was initially described in humans in 1966 after being isolated from a soldier in Panama who had a fever, headache, myalgia and leukopenia PTV, a mosquito-borne bunyavirus, usually causes a mild and self-limited infection in humans, but can progress to acute febrile illness. In both human and animal infections, the genetic determinants of the host probably contribute to the pathogenesis of flebovirus


REFERENCES

  1. Gundacker N, Carrera J, Castillo M, Díaz Y, Valenzuela J, Tamhane A et al. Clinical manifestations of Punta Toro virus species complex infections, Panama, 2009. Emerg Infect Dis. 2017; 23 (5): 872-874.

  2. Palacios G, Wiley M, Travassos A, Guzman H, Quiroz E et al. Characterization of the Punta Toro species complex (genus Phlebovirus, family Bunyaviridae). J Gen Virol. 2015; 96: 2079-2085.

  3. Stefan C, Chase K, Coyne S, Kulesh D, Minogue T et al. Development of real-time reverse transcriptase qPCR assays for the detection of Punta Toro virus and Pichinde virus. Virol J. 2016; 13: 54.

  4. Mendenhalla M, Wonga M, Skirpstunas R, Morreya J, Gowena B. Punta Toro Virus (Bunyaviridae, Phlebovirus) infection in mice: strain differences in pathogenesis and host interferon response. Virology. 2009; 395 (1): 143-151.

  5. Ashleya S, Ameresa S, Gerrarda S, Foremand O, Eatona K, etal. Host genetic variation in susceptibility to Punta Toro Virus. Virus Res. 2011; 157 (1): 71-75.

  6. Xu F, Liang X, Tesh R, Xiao S. Characterization of cell-death pathways in Punta Toro virus-induced hepatocyte injury. J Gen Virol. 2008; 89: 2175-2181.

  7. Durána N, Gowenc B, Costa F, Justoe G, Brocchi M, Nunes O et al. A biotechnological product and its potential as a new immunomodulator for treatment of animal phlebovirus infection: Punta Toro virus. Antiviral Res. 2009; 83: 143-147.

  8. Gowena B, Wonga M, Junga K, Blattb L, Sidwella R. Prophylactic and therapeutic intervention of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with interferon Alfacon-1. Antiviral Res. 2008; 77(3): 215-224.




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