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Revista Mexicana de Mastología

ISSN 1870-2821 (Print)
Organo Oficial de la Asociación Mexicana de Mastología
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2020, Number 1

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Rev Mex Mastol 2020; 10 (1)

Metaplastic breast cancer of unusual location

Apodaca RI, Villegas CF, Hernández HB, Tenorio TJA, Ríos LNP, Bravo GDA, Llerena BLI, Díaz OJJ, Moreno FG
Full text How to cite this article 10.35366/95764

DOI

DOI: 10.35366/95764
URL: https://dx.doi.org/10.35366/95764

Language: Spanish
References: 5
Page: 25-27
PDF size: 180.70 Kb.


Key words:

Neoplasia, breast cancer, metaplastic.

ABSTRACT

Introduction: Metaplastic squamous cell carcinoma of the breast accounts for less than 1% of all invasive breast carcinomas. Case report: 47-year-old woman female with metaplastic carcinoma with epidermoid differentiation. Immunohistochemistry with estrogen receptors 30%, progesterone receptors 5%, Her2 negative, Ki 67 80%. A simple mastectomy is performed with wide skin resection and skin coverage with a dorsal flap. Definitive histopathological diagnosis: metaplastic carcinoma with epidermoid differentiation of 12 × 11 × 8 cm; invasion and skin ulceration, vascular, presence of lymphatic and perineural invasion, three supraclavicular lymph nodes with metastases and 21 axillary nodes with mixed hyperplasia. Conclusion: Metaplastic breast carcinoma is associated with indicators of poor prognosis, requiring an aggressive multidisciplinary care.


REFERENCES

  1. Graziano L, Graziano FP, Bitencourt AG, Soto DB, Hiro A, Nunes CC. Metaplastic squamous cell carcinoma of the breast: a case report and literature review. Rev Assoc Med Bras. 2016; 62 (7): 618-621. doi:10.1590/1806-9282.62.07.618.

  2. McKinnon E, Xiao P. Metaplastic carcinoma of the breast. Arch Pathol Lab Med. 2015; 139 (6): 819-822. doi:10.5858/arpa.2013-0358-rs.

  3. Song Y, Liu X, Zhang G, Song H, Ren Y, He X, Pang D. Unique clinicopathological features of metaplastic breast carcinoma compared with invasive ductal carcinoma and poor prognostic indicators. World J Surg Oncol. 2013; 11 (1): 129. doi:10.1186/1477-7819-11-129.

  4. Shah DR, Tseng WH, Martinez SR. Treatment options for metaplastic breast cancer. ISRN Oncol. 2012; 7061-7062.

  5. Tzanninis IG, Kotteas EA, Ntanasis-Stathopoulos I, Kontogianni P, Fotopoulos G. Management and outcomes in metaplastic breast cancer. Clin Breast Cancer. 2016; 16 (6): 437-443. doi: 10.1016/j.clbc.2016.06.002.




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Rev Mex Mastol. 2020;10