medigraphic.com
ISSN 0035-0052 (Print)

2020, Number 4

<< Back Next >>

Rev Mex Pediatr 2020; 87 (4)

Post mortem findings in neonates with Bochdalek diaphragmatic hernia

Padilla-Santamaría F, Ferman-Cano F, Siordia-Reyes AG, Maya-Franco L, Genis-Zárate JH

Language: Spanish
References: 19
Page: 137-141
PDF size: 261.85 Kb.


ABSTRACT

Introduction: Congenital diaphragmatic hernia is defined as the displacement of the abdominal organs into the chest cavity through a diaphragmatic defect. Within this type of hernias, the Bochdalek hernia is the most common. Objectives: To describe the autopsy findings of neonates with Bochdalek hernia, treated in a tertiary pediatric hospital, over 22 years. Material and methods: Retrospective study in which the autopsy protocols of neonates diagnosed with Bochdalek hernia, carried out between 1997 and 2019, were evaluated. These protocols were evaluated again by two pediatric pathologists, independently. Results: 18 autopsies (2.26%) were included. Twelve (66.7%) were total, and six partial autopsies. Ten infants were male (55.5%), and at the time of death, the median postnatal age was 2.5 days. In the majority, the diaphragmatic defect was on the left side (66.7%), and all presented pulmonary hypoplasia and pulmonary arterial hypertension (PAH). Heart disease was the most frequent congenital malformation (44.4%), followed by digestive and genitourinary malformations. Conclusions: In patients with hernia Bochdalek, secondary disorders (pulmonary hypoplasia and HAP) and congenital malformations are directly related morbidity and mortality.


REFERENCES

  1. Bolaños-Nava I. Hernia diafragmática congénita. Rev Mex Anestesiol. 2005; 28 (Supl.1): S126-S128.

  2. Pereira S, Ribeiro PV, Araujo N, Moreira D, Barbosa L. Congenital diaphragmatic hernia with delayed diagnosis: report of two cases. Case Rep Clin Med. 2015; 4: 114-118.

  3. Salas G, Reusmann A, Boglione M, Rubio M, Fumiere F, Fariña D. Hernia diafragmática congénita bilateral de diagnóstico tardío: reporte de un caso. Arch Argent Pediatr. 2016; 114 (1): e29-e31.

  4. Hamid KS, Rai SS, Rodriguez JA. Symptomatic Bochdalek hernia in an adult. JSLS. 2010;14 (2): 279-281. doi:10.4293/108680810X12785289144719

  5. Aziz A, Yasmin R, Haque MA. Bochdalek hernia in asymptomatic adults: a case report of radiological importance. J Bangladesh Coll Phys Surg. 2018; 36 (4): 175-178.

  6. Herling A, Makhdom F, Al-Shehri A, Mulder DS. Bochdalek hernia in a symptomatic adult. Ann Thorac Surg. 2014;98 (2): 701-704. doi:10.1016/j.athoracsur.2013.09.074

  7. Bracho-Blanchet E, Esperante-Lozano S, Dávila-Pérez R, Reed-López F, Zalles-Vidal C, Nieto-Zermeño J. Factores pronóstico para mortalidad en recién nacidos con hernia de Bochdalek. Estudio de casos y controles. Cir Cir. 2011; 79 (4): 305-311.

  8. Navarrete-Hernández E, Canún-Serrano S, Valdés-Hernández J, Reyes-Pablo AE. Malformaciones congénitas al nacimiento: México, 2008-2013. Bol Med Hosp Infant Mex. 2017; 74 (4): 301-308.

  9. Chandrasekharan PK, Rawat M, Madappa R, Rothstein DH, Lakshminrusimha S. Congenital diaphragmatic hernia-a review. Matern Health Neonatol Perinatol. 2017; 3: 6.

  10. Maggiolo J, Rubilar L, Girardi G, Pérez L. Hernia diafragmática en Pediatría. Neumol Pediatr. 2016; 11 (2): 85-89.

  11. Graham G, Connor P. Antenatal diagnosis of congenital diaphragmatic hernia. Semin Perinatol. 2005; 29 (2): 69-76.

  12. García-Posada R, Gómez O, Martínez JM, Puerto B, Gratacós E. Hernia diafragmática congénita: criterios pronósticos y estado actual del tratamiento prenatal. Guía clínica. Diagn Prenat. 2012; 23 (3): 126-133.

  13. Heath D, Edwards JE. The pathology of hypertensive pulmonary vascular disease. A description of six grades of structural changes in the pulmonary arteries with special reference to congenital cardiac septal defects. Circulation. 1958; 18: 533-547.

  14. Kattan J. Hernia diafragmática congénita: frontera entre ciencia básica y clínica. Rev Chil Pediatr. 2002; 73 (3): 229-238.

  15. García H, Aparicio-de la Luz S, Franco-Gutiérrez M, González-Lara D, González-Cabello H, Villegas-Silva R. Factores pronósticos asociados a mortalidad en recién nacidos con hernia diafragmática congénita. Gac Med Mex. 2003; 139 (1): 7-14.

  16. Van Dooren MF, Goemaere NNT, De Klein A, Tibboel D, De Krijger RR. Postmortem findings and clinicopathological correlation in congenital diaphragmatic hernia. Pediatr Dev Pathol. 2004; 7: 459-467.

  17. Borys D, Taxy JB. Congenital diaphragmatic hernia and chromosomal anomalies: autopsy study. Pediatr Dev Pathol. 2004; 7 (1): 35-38.

  18. Cohen MC, Drut R. La autopsia en pediatría. Diagnóstico de situación en un hospital de pediatría de referencia. Arch Argent Pediatr. 2003; 101 (3): 166-170.

  19. Ridaura-Sanz C, De León-Bojorge B, López-Corella E. SIDA en niños y adolescentes. Un estudio de 34 autopsias en dos décadas. Acta Pediatr Mex. 2007; 28 (6): 270-277.




2020     |     www.medigraphic.com