medigraphic.com
SPANISH

Medicina Interna de México

Colegio de Medicina Interna de México.
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 6

<< Back Next >>

Med Int Mex 2020; 36 (6)

Persistence of symptoms in patients after coronavirus disease (COVID-19) in a third level hospital of Puebla, Mexico

Herrera-García JC, Arellano-Montellano EI, Juárez-González LI, Contreras-Andrade RI
Full text How to cite this article

Language: Spanish
References: 19
Page: 789-793
PDF size: 204.59 Kb.


Key words:

Symptoms, COVID-19, Coronavirus.

ABSTRACT

Background: In the epidemic phase of the coronavirus in Mexico a phenomenon called persistent symptoms has been described, which occur in all patients who have developed the disease, but despite its improvement in time, they present a series of diverse symptoms that do not allow them to continue their daily life normally during the resolution phase of the disease.
Objective: To determine the persistence of post-COVID-19 symptoms in a population cared at a third level hospital of Puebla.
Material and Method: An observational and descriptive study of the population attended in the Pneumology outpatient clinic at Hospital Ángeles Puebla. Post- COVID 19 patients were asked a symptom questionnaire within 30-60 days after their symptoms or resolution of the symptoms under the following variables: age, sex, BMI, comorbidities, tobacco index, symptoms in acute COVID-19 infection, established treatment, days of resolution of symptoms, presence of symptoms after resolution of the disease.
Results:Fifty patients were included (30% women and 70% men), 84% presented persistent symptoms after the resolution of the disease, of which fatigue, headache, chest tightness and dyspnea were the main ones.
Conclusions: This work demonstrates in a population the importance of symptoms after COVID-19 infection, which are of clinical relevance for the total resolution of the disease and aimed at improving the quality of life of recovered patients.


REFERENCES

  1. Carfì A, Bernabei R, Landi FGemelli Against COVID-19 Post- Acute Care Study Group, for the Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute covid-19. JAMA 2020; 9. doi: 10.1001/ jama.2020.12603

  2. Post-hospitalisation covid-19 study. www.phosp.org.

  3. Wise J. Covid-19: Symptoms are common after acute phase of disease, Italian study shows. BMJ 2020; 370: m2804. http://dx.doi.org/10.1136/bmj.m2804

  4. Hopkins C, Surda P, Whitehead E, et al. Early recovery following new onset anosmia during the COVID-19 pandemic – an observational cohort study. J Otolaryngol Head Neck Surg 2020; 49. https://doi.org/10.1186/s40463-020- 00423-8

  5. Arons MM, Hatfield KM, Reddy SC, Kimball A, James A, Jacobs JR, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med 2020; 382 (22): 2081-2090. doi:10.1056/NEJMoa2008457

  6. Bullard J, Durst K, Funk D, Strong JE, Alexander D, Garnett L, et al. predicting infectious SARS-CoV-2 from diagnostic samples. Clin Infect Dis 2020. doi: 10.1093/cid/ciaa638

  7. Cheng HW, Jian SW, Liu DP, Ng TC, Huang WT, Lin HH, et al. Contact tracing assessment of covid-19 transmission dynamics in Taiwan and risk at different exposure periods before and after symptom onset. JAMA Intern Med 2020. doi:10.1001/jamainternmed.2020.2020

  8. Kiyuka PK, Agoti CN, Munywoki PK, Njeru R, Bett A, Otieno JR, et al. Human coronavirus NL63 molecular epidemiology and evolutionary patterns in rural coastal Kenya. J Infect Dis 2018; 217 (11): 1728-1739. doi: 10.1093/infdis/jiy098

  9. Korea Centers for Disease Control and Prevention. Findings from Investigation and Analysis of re-positive cases. May 19, 2020. Available at: https://www.cdc.go.kr/board/ board.es?mid=a30402000000&bid=0030&act=view&li st_no=367267&nPage=1external icon

  10. Li N, Wang X, Lv T. Prolonged SARS-CoV-2 RNA shedding: not a rare phenomenon. J Med Virol 2020. doi: 10.1002/jmv.25952

  11. Liu WD, Chang SY, Wang JT, Tsai MJ, Hung CC, Hsu CL, et al. Prolonged virus shedding even after seroconversion in a patient with COVID-19. J Infect 2020; S0163-4453 (20) 30190-0. doi: 10.1016/j.jinf.2020.03.063

  12. Lu J, Peng J, Xiong Q, Liu Z, Lin H, Tan X, et al. Clinical, immunological and virological characterization of COVID- 19 patients that test re-positive for SARS-CoV-2 by RT-PCR. (Preprint) Medrxiv. 2020. doi: https://doi. org/10.1101/2020.06.15.20131748

  13. Midgley CM, Kujawski SA, Wong KK, Collins, JP, Epstein L, Killerby ME et al. Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States. Nat Med 2020; 26 (6): 861-868. doi: 10.1038/s41591-020-0877-5

  14. Quicke K, Gallichote E, Sexton N, Young M, Janich A, Gahm G, et al. Longitudinal surveillance for SARS-CoV-2 RNA among asymptomatic staff in five Colorado skilled nursing facilities: epidemiologic, virologic and sequence analysis. (Preprint) Medrxiv. 2020. doi: https://doi.org/10.1101/20 20.06.08.20125989external icon

  15. van Kampen J, van de Vijver D, Fraaij P, Haagmans B, Lamers M, Okba N, et al. Shedding of infectious virus in hospitalized patients with coronavirus disease-2019 (COVID-19): duration and key determinants. (Preprint) Medrxiv. 2020. doi: https://doi.org/10.1101/2020.06.08.20125310

  16. Wölfel R, Corman VM, Guggemos W, Seilmaier M, Zange S, Müller MA, et al. Virological assessment of hospitalized patients with COVID-2019. Nature 2020; 581 (7809): 465- 469. doi:10.1038/s41586-020-2196-x

  17. Xiao F, Sun J, Xu Y, Li F, Huang X, Li H, et al. Infectious SARS-CoV-2 in feces of patient with severe COVID-19. Emerg Infect Dis 2020; 26 (8): 10.3201/eid2608.200681. doi:10.3201/eid2608.200681

  18. Young BE, Ong SWX, Kalimuddin S, Low JG, Ta, SY, Loh J, et al. Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore. JAMA 2020; 323 (15): 1488-1494. doi:10.1001/jama.2020.3204

  19. Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med 2020; 382 (12): 1177-1179. doi: 10.1056/NEJMc200173




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Med Int Mex. 2020;36