Murillo SMF, Jiménez AS, Kagi BM

Language: Spanish
References: 19
Page: 1-11
PDF size: 217.69 Kb.

ABSTRACT

Intrahepatic cholestasis of pregnancy is a hepatic disease that appears commonly in the second or third trimester, it is characterized by pruritus predominantly in palms and soles with disturbed liver function tests, being the increasing serum bile acids the most sensitive disturbance and usually resolves after delivery. The etiology involves hormonal, environmental and genetic factors and it is associated with complications such as preterm labor, fetal distress, meconium staining and intrauterine fetal death. The aim of treatment is to reduce symptoms and prevent maternal and fetal complications. Ursodeoxycholic acid is the treatment of choice because is the most effective, safe and it has demonstrated benefits.

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