medigraphic.com
ISSN 0185-6014 (Print)
Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2020, Number 3

<< Back

Rev Mex Patol Clin Med Lab 2020; 67 (3)

Metastatic papillary carcinoma to the neck, thinking beyond the thyroid gland

Duque CS, Moreno A, Serna OC, Agudelo M

Language: English
References: 10
Page: 161-164
PDF size: 258.87 Kb.


ABSTRACT

Introduction: A description of a male patient with prior treatment for a right lung adenocarcinoma and a close follow-up for a right thyroid lobe 7 mm papillary cancer, who developed massive right neck metastasis. Objective: To describe the diagnostic dilemma to confirm or rule out the origin of the multiple neck metastasis to avoid unnecessary treatments. Methods: The biopsies from the lung, thyroid and neck tissues were reviewed and examined with immunohistochemistry. Results: The neck metastasis originated from an adenocarcinoma of the lung with papillary features. Conclusions: Unnecessary radioactive iodine treatments were avoided, thanks to the tumor markers.


REFERENCES

  1. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE et al. American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016; 26 (1): 1-133.

  2. Bertagan F, Albano D, Giovanella L, Bonacia M, Durmo R, Giubbini R, Treglia G. 68 Ga-Psma Pet thyroid incidentalomas hormones (Athens). 2019; 18 (2): 145-149.

  3. Chih-Yu Hsu BM, Ching-Ling Lin. Thyroid fine-needle aspiration cytology mimicking thyroid papillary cancer in a lung cancer patient. Diagnostic Cytopathology. 2017; 45 (3).

  4. Haraguchi S. Hioki M. Metastasis to the thyroid from lung adenocarcinoma mimicking thyroid carcinoma. J Thoracic Cardiovascular Surgery. 2004; 52 (7): 353-356.

  5. López F, Rodrigo JP, Silver CE, Haigentz M, Bishop JA, Strojan P et al. Cervical lymph node metastases from remote primary tumor sites: cervical lymph node metastases from a non-head and neck primary. Eisele D, editor. Head Neck. 2016; 38 (S1): E2374-E2385.

  6. Davis RS, Flynn MB, Moore C. An unusual presentation of carcinoma of the lung: 26 patients with cervical node metastases. J Surg Oncol. 1977; 9: 503-507.

  7. Carlson ER, Reddi SP, Monteleone KL. Metastatic lung cancer of the neck: Report of 2 cases. J Oral Maxillofac Surg. 2002; 60 (9): 1057-1061.

  8. Howlader N, Noone AM, Krapcho M, et al (eds). SEER Cancer Statistics Review, 1975-2016, National Cancer Institute, Bethesda, MD. [April 2019] https://seer.cancer.gov/csr/1975_2016/, based on November 2018 SEER data submission, posted to the SEER website.

  9. Sathiyamoorthy S. Maleki Z. Cytomorphologic overlap of differentiated thyroid carcinoma and lung adenocarcinoma and diagnostic value of TTF-1 and TGB on cytologic material. Diagn Cytopathol. 2014; 42 (1): 5-10.

  10. Chiang A, Detterbeck FC, Stewart T, Decker RH, Tanoue L. Chapter 48: Non-small cell lung cancer. In: DeVita VT, Lawrence TS, Rosenberg SA, eds. DeVita, Hellman, and Rosenberg’s cancer: principles and practice of oncology. 11th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2019. pp. 618-670.




2020     |     www.medigraphic.com