2002, Number 5
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Rev Mex Pediatr 2002; 69 (5)
Viral agents in children hospitalized by lower respiratory infections
Muraira GA, Villarreal CE, Quiroga GA, Ábrego MV, Durán RAG, Cárdenas CBG, Flores CO, Aranda SCM
Language: Spanish
References: 22
Page: 185-189
PDF size: 50.37 Kb.
ABSTRACT
Objective. The principal aim was to investigate the viral etiology of lower respiratory infections in children hospitalized in two winter seasons.
Method. One hundred and one children hospitalized with lower respiratory infections were tested by a indirect immunofluorescence technique for respiratory syncytial virus (RSV) parainfluenza, adenovirus and influenza virus, using nasopharyngeal aspirates. Also it was studied the risk severity in infants below 3 months age and those born prematurely.
Results. Virus was identified in 31cases (30.7%). The most frequent were: RSV, with 19 cases (61.3%), after 9 parainfluenza (29.0%), 2 adenovirus (6.5%), and 1 influenza (3.2%). In patients up 3 months old, there was trend toward more severe disease. Bronchopulmonary dysplasia was found in 5 patients, 3 required intensive care and the mean days of hospitalization was 14.7 vs 4.35, from 12 cases without dysplasia in intensive care unit.
Conclusions. Respiratory syncytial virus was principal viral agent detected. The patients younger than 6 months and gestational age less than 35 weeks had more hospital days. Children with bronchopulmonary dysplasia and infants below 3 months old are at risk for severe illness.
REFERENCES
Fete TJ, Noyes B. Common (but not always considered) viral infections of the lower respiratory tract. Pediatr Ann (United States) 1996; 25: 577-84.
The Impact-RSV Study Group. Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. Pediatrics 1998; 102: 531-537.
García J. Epidemiology of acute bronchopulmonary infection in children. Rev Prat 1996; 46: 2056-61.
Boyer MK, Cherry DJ. Neumonía no bacteriana. En: Feigin DR, Cherry DJ. Tratado de infecciones en pediatría. Tercera ed. México: Nueva Editorial Interamericana McGraw-Hill 1995; 1: 285-296.
Darville T, Yamauchi T. Respiratory syncytial virus. Pediatrics in Review 1998; 19: 55-62.
Muraira-Gutiérrez A, Quiroga-Garza A, Villarreal-Castellanos E, Abrego-Moya V, Flores-Caloca O, Aranda-Saro MC. Virus sincicial respiratorio en la temporada invernal 1999-2000 en la ciudad de Monterrey, Nuevo León, México. Bol Med Hosp Infant Mex 2001; 58: 441-7.
American Academy of Pediatrics. Parainfluenza. In: Pickering LK, ed 2000 Red Book: Report of the Committee on Infections Diseases. 25th ed. Elk Grove Village, Ill: American Academy of Pediatrics 2000; 576-578.
American Academy of Pediatrics. Adenovirus. In: Pickering LK, ed 2000 Red Book: Report of the Committee on Infections Disease. 25 ed. Elk Grove Village, Ill: American Academy of Pediatrics 2000; 214-217.
American Academy of Pediatrics. Influenza. In: Pickering LK, ed 2000 Red Book: Report of the Committee on Infections Disease. 25th ed. Elk Grove Village, Ill: American Academy of Pediatrics 2000; 486-497.
IMAGEN Respiratory Screen. DAKO Ltd. Denmark House, Angel Drove, Ely, Cambridgeshire, CB7 4ET United Kingdom. Revision January 1999.
Sokol MD, Demmler JG. Diagnóstico viral rápido. En: Feigin-Cherry, ed. Tratado de infecciones en pediatría. 3 México: Nueva editorial Interamericana S.A. de C.V. 1995: 2634-2649.
Chan PW, Goh AY, Chua KB, Kharullah NS, Hool PS. Viral etiology of lower respiratory tract infection in young Malaysian children. J Paediatr Child Health (Australia) 1999; 35: 287-90.
Heiskanen-Kosma T, Korppi M, Jokinen C, Kurki S, Heiskanen L, Juvonen H, Kallinen S, Sten M, Tarkiainen A, Ronnberg PR, Kleem M, Makela PH, Leinonen M. Etiology of childhood pneumonia: serologic results of a prospective population-based study. Pediatr Infect Dis J 1998; 17: 986-91.
Levy BT, Graber MA. Respiratory syncytial virus infection in infants and young children. J Fam Pract 1997; 45: 473-81.
Perlstein HP, Kotagal RU, Bolling C, Steele R, Schoettker JP, Atherton DH, Farrell KM. Evaluation of an evidence-based guideline for bronchiolitis. Pediatrics 1999; 104: 1334-1341.
Goyenechea A, Bello M, Clua A, Savon C, Valdivia A, Oropesa S, Diaz O, Hernández B. Determination of complement-fixing antibodies to respiratory syncytial virus. Longitudinal study in a population of less than 1 year of age in the city of Havana. Rev Cubana Med Trop (Cuba) 1994; 46: 79-85.
Fisher RG, Gruber WC, Edwards KM, Reed GW, Tollefson SJ, Thompson JM, Wright PF. Twenty years of outpatient respiratory syncytial virus infection: framework for vaccine efficacy trials. Pediatrics 1997; 99: (2) p E 7.
Videla C, Carballal G, Misirlian A, Aguilar M. Acute lower respiratory infections due to respiratory syncytial virus and adenovirus among hospitalized children from Argentina. Clin Diagn Virol (Netherlands) 1998; 10: 17-23.
Carballal G, Videla GM, Espinoza MA, Savy V, Vez O, Sequeira MD, Knez V, Requeijo PV, Posse CR, Miceli J. Infections in children from four cities of Argentina 1993-1994. J Med Virol 2001; 64: 167-74.
Kappagoda C, Isaacs D, Mellis C, Peat J, De Silva L, O’Connell A. Critical influenza virus infection. J Paediatr Child Health 2000; 36: 318-21.
Kobashi Y, Ohba H, Yoneyama H, Okimoto N, Soejima R. Comparison of community-acquired pneumonia in relation to influenza A and RS virus infections. Kansenshogaku Zasshi 2001; 75: 42-7.
Tammela OK. First-year infections after initial hospitalization in low birth weight infants with and without bronchopulmonary dysplasia. Scand J Infect Dis 1992; 24: 515-24.