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2020, Number 4

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Rev Latin Infect Pediatr 2020; 33 (4)

Madariaga Virus (MADV): a latent encephalitis for Latin America

Zúñiga CIR, Caro LJ

Language: Spanish
References: 6
Page: 174-177
PDF size: 114.04 Kb.


ABSTRACT

Madariaga Virus (MADV), formerly known as Eastern Equine Encephalitis Virus, is a single-stranded positive-sense RNA virus (family Togaviridae, genus Alphavirus) transmitted by mosquitoes. In Central and South America it gives rise to a spectrum of diseases in humans, ranging from undifferentiated fevers to fatal encephalitis and hemorrhage. The mosquitoes of the Culex species, subgenus Melanoconion, have been attributed as enzootic vectors in Latin America. In wildlife it has been found in rodents of the genus Oryzomys, common opossum Didelphis marsupialis, several species of birds and in snakes.


REFERENCES

  1. Vittor AY, Armien B, Gonzalez P, Carrera JP, Dominguez C, Valderrama A et al. Epidemiology of emergent madariaga encephalitis in a region with endemic venezuelan equine encephalitis: initial host studies and human cross-sectional study in Darien, Panama. PLoS Negl Trop Dis, 2016; 10 (4): 1-20.

  2. Arrigo N, Weaver S. In the genus Alphavirus, create a species named Madariaga virus comprising some of the virus strains currently classified in the species Eastern equine encephalitis virus. Available in: https://talk.ictvonline.org/files/ictv_official_taxonomy_updates_since_the_8th_report/m/vertebrate-official/4488 Consultado el 12/03/2019.

  3. Blohm G, Lednicky J, White S, Mavian C, Márquez M. Madariaga virus: identification of a lineage III strain in a venezuelan child with acute undifferentiated febrile illness, in the setting of a possible equine epizootic. Clin Infec Dis. 2018; 67 (4): 619-621.

  4. Luciani K, Abadía I, Martínez A, Cisneros J, Guerra I, García M et al. Case report: Madariaga virus infection associated with a case of acute disseminated encephalomyelitis. Am J Trop Med Hyg. 2015; 92 (6): 1130-1132.

  5. Silva M, Auguste A, Terzian A, Vedovello D, Riet F. Isolation and characterization of Madariaga Virus from a horse in Paraíba State, Brazil. Transbound Emerg Dis. 2017; 64 (3): 990-993.

  6. Madrid D, Pagoaga A, Barahona J. Encefalitis Viral: Una Gran Simuladora. Rev Hon Pos Psiq. 2016; 1: 9-15.




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